cad a22 4500 357735773 20181103044139.0 cr unu---uuuuu 160303s2015 xx s 000 0 eng 10.5167/uzh-123200 doi 10.1101/cshperspect.a020396 doi (ZORA)oai:www.zora.uzh.ch:123200 570 ddc 610 ddc Weber Bruno The Astrocyte: Powerhouse and Recycling Center [Elektronische Daten] [Bruno Weber, L Felipe Barros] closedAccess eu-repo Brain metabolism is characterized by fuel monodependence, high-energy expenditure, autonomy from the rest of body, local recycling, and marked division of labor between cell types. Although neurons spend most of the brain's energy on signaling, astrocytes bear the brunt of the metabolic load, controlling the composition of the interstitial fluid, supplying neurons with energy substrates and precursors for biosynthesis, and recycling neurotransmitters, oxidized scavengers, and other waste products. Outstanding questions in this field are the role of oligodendrocytes, the metabolic behavior of the different subtypes of astrocytes during development and disease, and the emerging notion that metabolism may participate directly in information processing. Institute of Pharmacology and Toxicology zora Barros L Felipe joint author Cold Spring Harbor Perspectives in Biology 7:online https://www.zora.uzh.ch/id/eprint/123200/1/Cold%20Spring%20Harb%20Perspect%20Biol-2015-Weber-.pdf text/html WWW-Backlink auf das Repository 1 Journal Article PeerReviewed zora ZORA 856 40 https://www.zora.uzh.ch/id/eprint/123200/1/Cold%20Spring%20Harb%20Perspect%20Biol-2015-Weber-.pdf text/html WWW-Backlink auf das Repository ZORA 100 1- Weber Bruno ZORA 700 1- Barros L Felipe joint author ZORA 773 0- Cold Spring Harbor Perspectives in Biology 7:online BK010053 XK010053 XK010000 ZORA ZORA ZORA Journal Article closedAccess