Hepatitis B Virus HBx Peptide 116-138 and Proteasome Activator PA28 Compete for Binding to the Proteasome α4/MC6 Subunit
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| 024 | 7 | 0 | |a 10.1515/BC.2003.005 |2 doi |
| 035 | |a (NATIONALLICENCE)gruyter-10.1515/BC.2003.005 | ||
| 245 | 0 | 0 | |a Hepatitis B Virus HBx Peptide 116-138 and Proteasome Activator PA28 Compete for Binding to the Proteasome α4/MC6 Subunit |h [Elektronische Daten] |c [R. Stohwasser, H.-G. Holzhütter, U. Lehmann, P. Henklein, P.-M. Kloetzel] |
| 520 | 3 | |a PA28 is a modulator of the 20S proteasome. The PA28 binding sites on the 20S proteasome are still not well defined. Using yeast two-hybrid interaction assays and proteasome inactivation kinetics we provide evidence that the proteasome α4 subunit is one of the PA28 binding sites. This finding is supported by the observation that a hepatitis Bvirus X protein-derived polypeptide habouring the α4 proteasome subunit binding motif impairs the activation of 20S proteasomes by PA28. | |
| 540 | |a Copyright © 2003 by Walter de Gruyter GmbH & Co. KG | ||
| 690 | 7 | |a Biochemistry |2 nationallicence | |
| 690 | 7 | |a Molecular biology |2 nationallicence | |
| 690 | 7 | |a Cellular biology |2 nationallicence | |
| 700 | 1 | |a Stohwasser |D R. |4 aut | |
| 700 | 1 | |a Holzhütter |D H.-G |4 aut | |
| 700 | 1 | |a Lehmann |D U. |4 aut | |
| 700 | 1 | |a Henklein |D P. |4 aut | |
| 700 | 1 | |a Kloetzel |D P.-M |4 aut | |
| 773 | 0 | |t Biological Chemistry |d Walter de Gruyter |g 384/1(2003-01-27), 39-49 |x 1431-6730 |q 384:1<39 |1 2003 |2 384 |o bchm | |
| 856 | 4 | 0 | |u https://doi.org/10.1515/BC.2003.005 |q text/html |z Onlinezugriff via DOI |
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1515/BC.2003.005 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Stohwasser |D R. |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Holzhütter |D H.-G |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Lehmann |D U. |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Henklein |D P. |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kloetzel |D P.-M |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Biological Chemistry |d Walter de Gruyter |g 384/1(2003-01-27), 39-49 |x 1431-6730 |q 384:1<39 |1 2003 |2 384 |o bchm | ||
| 900 | 7 | |b CC0 |u http://creativecommons.org/publicdomain/zero/1.0 |2 nationallicence | |
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| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-gruyter | ||