Stable microbubble test and click test to predict respiratory distress syndrome in preterm infants not requiring ventilation at birth

Verfasser / Beitragende:
[H. H. Fiori, I. Varela, A. L. Justo, R. M. Fiori]
Ort, Verlag, Jahr:
2003
Enthalten in:
Journal of Perinatal Medicine, 31/6(2003-11-20), 509-514
Format:
Artikel (online)
ID: 378851098
LEADER caa a22 4500
001 378851098
003 CHVBK
005 20180305123323.0
007 cr unu---uuuuu
008 161128e20031120xx s 000 0 eng
024 7 0 |a 10.1515/JPM.2003.077  |2 doi 
035 |a (NATIONALLICENCE)gruyter-10.1515/JPM.2003.077 
245 0 0 |a Stable microbubble test and click test to predict respiratory distress syndrome in preterm infants not requiring ventilation at birth  |h [Elektronische Daten]  |c [H. H. Fiori, I. Varela, A. L. Justo, R. M. Fiori] 
520 3 |a Aims: To determine the usefulness of the stable microbubble test (SMT) and of the click test (CT) on gastric aspirates obtained soon after birth to predict respiratory distress syndrome (RDS) in preterm babies not requiring ventilation at birth. Patients and methods: The study was carried out with a cohort between 24 and 34 weeks of gestational age. Gastric secretions were collected before 1 hour of life and frozen for further analysis. Results: 110 neonates were studied. For a cut-off value ≤ 10 microbubbles/mm2 (mb/mm2) the sensitivity and specificity to predict RDS were 73.9% and 92%, respectively, in the SMT. The best SMT cut-off point to predict RDS was ≤ 15 mb/mm2 (sensitivity = 82.6%;specificity = 85.1%) if equal weight was given to false-positive and false-negative results. CT (104 samples) showed a sensitivity of 100% and a specificity of 45.1% to predict RDS. The overall accuracy of the SMT was better than the overall accuracy of the CT (87.5% vs. 64.4%; p < 0.001) to predict RDS. Conclusions: The SMT is more accurate than the CT to predict RDS in infants below 35 weeks of gestational age and may be helpful to select patients to receive surfactant. 
540 |a Copyright © 2003 by Walter de Gruyter GmbH & Co. KG 
690 7 |a Human reproduction, growth & development  |2 nationallicence 
690 7 |a Gynaecology & obstetrics  |2 nationallicence 
690 7 |a Paediatric medicine  |2 nationallicence 
700 1 |a Fiori  |D H. H.  |4 aut 
700 1 |a Varela  |D I.  |4 aut 
700 1 |a Justo  |D A. L.  |4 aut 
700 1 |a Fiori  |D R. M.  |4 aut 
773 0 |t Journal of Perinatal Medicine  |d Walter de Gruyter  |g 31/6(2003-11-20), 509-514  |x 0300-5577  |q 31:6<509  |1 2003  |2 31  |o jpme 
856 4 0 |u https://doi.org/10.1515/JPM.2003.077  |q text/html  |z Onlinezugriff via DOI 
908 |D 1  |a research article  |2 jats 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1515/JPM.2003.077  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Fiori  |D H. H.  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Varela  |D I.  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Justo  |D A. L.  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Fiori  |D R. M.  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Journal of Perinatal Medicine  |d Walter de Gruyter  |g 31/6(2003-11-20), 509-514  |x 0300-5577  |q 31:6<509  |1 2003  |2 31  |o jpme 
900 7 |b CC0  |u http://creativecommons.org/publicdomain/zero/1.0  |2 nationallicence 
898 |a BK010053  |b XK010053  |c XK010000 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-gruyter