Neopterin Profile to Evaluate the Effectiveness of Treatment in Aggressive Periodontitis
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| 024 | 7 | 0 | |a 10.1515/pteridines.2003.14.3.77 |2 doi |
| 035 | |a (NATIONALLICENCE)gruyter-10.1515/pteridines.2003.14.3.77 | ||
| 245 | 0 | 0 | |a Neopterin Profile to Evaluate the Effectiveness of Treatment in Aggressive Periodontitis |h [Elektronische Daten] |c [Aysen Bodur, Terken Baydar, Nurdan Ozmeric, Ayse Basak Engin, Ahu Uraz, Kaya Eren, Gonul Sahin] |
| 520 | 3 | |a Periodontal disease results from the interaction of the host defence mechanisms with the microbial dental plaque. Analysis of gingival crevicular Huid (GCF) provides a non-invasive means of evaluating the role of the host response in periodontal disease. Based on our previous study, demonstrating increased levels of neopterin in GCF and saliva from patients with aggressive periodontitis (AgP), the aim of this study was to evaluate the effect of periodontal treatment on the levels of neopterin in GCF, saliva and urine of patients with AgP. Pre-treatment values of neopterin in GCF were 4.04 ± 0.86 nmol/ml for the AgP group (n=8) and 2.68 ± 0.90 nmol/ml fyr the control group (n=8; difference not significant). After periodontal treatment, the level of ncoptei in was found 2.38 ± 0.72 nmol/ml in the patient group which did not differ f r om pre-treatment levels. The salivary neopterin concentration was higher in both AgP groups (14.14 ± 2.85 nmol/1 and 8.02 ± 3.12 nmol/1, before and after periodontal treatment) than in controls (2.58 ± 0.3 nmol/1; both p<0.05). No significant difference in salivary neopterin level was observed in patients before and after periodontal treatment. Concentrations of urine neopterin in patients before treatment were 188.5 ± 30.98 μηιοί neopterin/mol creatinine and 168.1 + 20.21 μηιοί in controls (difference not significant). Following periodontal treatment, the urinary neopterin levels (310.1 ± 39.82 μηιοί neopterin/mol creatinine) were higher when compared to the baseline levels and to controls (p<0.05). Our results suggest that neopterin in saliva and GCF might be associated with the periodontal diseases process. | |
| 540 | |a © 2013 by Walter de Gruyter GmbH & Co. | ||
| 690 | 7 | |a neopterin |2 nationallicence | |
| 690 | 7 | |a gingival crevicular fluid |2 nationallicence | |
| 690 | 7 | |a saliva |2 nationallicence | |
| 690 | 7 | |a urine |2 nationallicence | |
| 690 | 7 | |a aggressive periodontitis |2 nationallicence | |
| 700 | 1 | |a Bodur |D Aysen |u Department of Peri odontology, Faculty of Dentistry, Gazi University, 06510 Ankara, Turkey |4 aut | |
| 700 | 1 | |a Baydar |D Terken |u Department of Toxicology, Faculty of Pharmacy, Hacettepe University, 06100 Ankara, Turkey |4 aut | |
| 700 | 1 | |a Ozmeric |D Nurdan |u Department of Peri odontology, Faculty of Dentistry, Gazi University, 06510 Ankara, Turkey |4 aut | |
| 700 | 1 | |a Engin |D Ayse Basak |u Department of Toxicology, Faculty of Pharmacy, Hacettepe University, 06100 Ankara, Turkey |4 aut | |
| 700 | 1 | |a Uraz |D Ahu |u Department of Peri odontology, Faculty of Dentistry, Gazi University, 06510 Ankara, Turkey |4 aut | |
| 700 | 1 | |a Eren |D Kaya |u Department of Peri odontology, Faculty of Dentistry, Gazi University, 06510 Ankara, Turkey |4 aut | |
| 700 | 1 | |a Sahin |D Gonul |u Department of Toxicology, Faculty of Pharmacy, Hacettepe University, 06100 Ankara, Turkey |4 aut | |
| 773 | 0 | |t Pteridines |d De Gruyter |g 14/3(2003-08), 77-81 |x 0933-4807 |q 14:3<77 |1 2003 |2 14 |o pteridines | |
| 856 | 4 | 0 | |u https://doi.org/10.1515/pteridines.2003.14.3.77 |q text/html |z Onlinezugriff via DOI |
| 908 | |D 1 |a research article |2 jats | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1515/pteridines.2003.14.3.77 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Bodur |D Aysen |u Department of Peri odontology, Faculty of Dentistry, Gazi University, 06510 Ankara, Turkey |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Baydar |D Terken |u Department of Toxicology, Faculty of Pharmacy, Hacettepe University, 06100 Ankara, Turkey |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ozmeric |D Nurdan |u Department of Peri odontology, Faculty of Dentistry, Gazi University, 06510 Ankara, Turkey |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Engin |D Ayse Basak |u Department of Toxicology, Faculty of Pharmacy, Hacettepe University, 06100 Ankara, Turkey |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Uraz |D Ahu |u Department of Peri odontology, Faculty of Dentistry, Gazi University, 06510 Ankara, Turkey |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Eren |D Kaya |u Department of Peri odontology, Faculty of Dentistry, Gazi University, 06510 Ankara, Turkey |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Sahin |D Gonul |u Department of Toxicology, Faculty of Pharmacy, Hacettepe University, 06100 Ankara, Turkey |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Pteridines |d De Gruyter |g 14/3(2003-08), 77-81 |x 0933-4807 |q 14:3<77 |1 2003 |2 14 |o pteridines | ||
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