Application of toxicogenomics to the endocrine disruption issue
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| 024 | 7 | 0 | |a 10.1351/pac200375112419 |2 doi |
| 035 | |a (NATIONALLICENCE)gruyter-10.1351/pac200375112419 | ||
| 245 | 0 | 0 | |a Application of toxicogenomics to the endocrine disruption issue |h [Elektronische Daten] |c [T. Shirai, Makoto Asamoto] |
| 520 | 3 | |a Toxicogenomics can be expected to be a useful method for detecting the carcinogenic potential of endocrine active substances (EASs) in the short term with the generation of understanding of mode-of-action and mechanisms when a reliable database with information about proteomics and informatics is established. At present, there are no concrete epidemiological data supporting any exogenous EAS contribution to hormone-related organ carcinogenesis in humans. However, with the establishment of appropriate animal models and analysis of genomic-scale gene expression, risk identification and evaluation should be facilitated within a relatively short period, and this approach eventually promises to contribute a great deal of risk management regarding EASs. | |
| 540 | |a © 2013 Walter de Gruyter GmbH, Berlin/Boston | ||
| 700 | 1 | |a Shirai |D T. |u Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, 1-Kawasumi, Nagoya 467-8601, Japan |4 aut | |
| 700 | 1 | |a Asamoto |D Makoto |u Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, 1-Kawasumi, Nagoya 467-8601, Japan |4 aut | |
| 773 | 0 | |t Pure and Applied Chemistry |d De Gruyter |g 75/11-12(2003-01-01), 2419-2422 |x 0033-4545 |q 75:11-12<2419 |1 2003 |2 75 |o pac | |
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| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Shirai |D T. |u Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, 1-Kawasumi, Nagoya 467-8601, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Asamoto |D Makoto |u Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, 1-Kawasumi, Nagoya 467-8601, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Pure and Applied Chemistry |d De Gruyter |g 75/11-12(2003-01-01), 2419-2422 |x 0033-4545 |q 75:11-12<2419 |1 2003 |2 75 |o pac | ||
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