caa a22 4500 378861956 CHVBK 20180305123348.0 cr unu---uuuuu 161128e20030101xx s 000 0 eng 10.1351/pac200375112197 doi (NATIONALLICENCE)gruyter-10.1351/pac200375112197 Matthiessen P. Centre for Ecology and Hydrology, Lancaster Environment Centre, Library Avenue, Bailrigg, Lancaster LA1 4AP, UK Historical perspective on endocrine disruption in wildlife [Elektronische Daten] [P. Matthiessen] Endocrine disruption (ED) as a named field of research has been very active for over 10 years, but effects in wildlife that would now be labeled as ED have been studied since the 1940s. This paper briefly surveys the progress in wildlife studies that has been made to date and draws out the major themes and issues that have been identified. In particular, it discusses information concerning causative substances, modes of action, ubiquity of effects across taxa, individual- and population-level impacts, and the importance of low-dose and mixture effects. The main conclusion is that while most wildlife taxa are showing some ED effects at some locations, good evidence for population-level impacts is still limited to a few groups. In order to improve both the interpretation of field observations and the way in which environmental risk assessments are conducted, we need to develop an enhanced ability to predict effects on populations and communities from a knowledge of effects on individuals. © 2013 Walter de Gruyter GmbH, Berlin/Boston Pure and Applied Chemistry De Gruyter 75/11-12(2003-01-01), 2197-2206 0033-4545 75:11-12<2197 2003 75 pac https://doi.org/10.1351/pac200375112197 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1351/pac200375112197 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Matthiessen P. Centre for Ecology and Hydrology, Lancaster Environment Centre, Library Avenue, Bailrigg, Lancaster LA1 4AP, UK NATIONALLICENCE 773 0- Pure and Applied Chemistry De Gruyter 75/11-12(2003-01-01), 2197-2206 0033-4545 75:11-12<2197 2003 75 pac CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter