caa a22 4500 378862073 CHVBK 20180305123349.0 cr unu---uuuuu 161128e20030101xx s 000 0 eng 10.1351/pac200375112207 doi (NATIONALLICENCE)gruyter-10.1351/pac200375112207 Endocrine disruption in invertebrates [Elektronische Daten] [J. Oehlmann, U. Schulte-Oehlmann] Recent reports have shown that a number of xenobiotics in the environment are capable of interfering with the normal endocrine function in a variety of animals. The overwhelming majority of the studies on the effects of hormone-mimetic industrial chemicals were focused on findings in vertebrates. More detailed information about the effects on and mechanisms of action in invertebrates has only been obtained from a few cases, although invertebrates represent more than 95 % of the known species in the animal kingdom and are extremely important with regard to ecosystem structure and function. The limited number of examples for endocrine disruption (ED) in invertebrates is partially due to the fact that their hormonal systems are rather poorly understood in comparison with vertebrates. Deleterious endocrine changes following an exposure to certain compounds may easily be missed or simply be unmeasurable at present, even though a number of studies show that endocrine disruption has probably occurred. The well-documented case studies of tributyltin effects in mollusks and of insect growth regulators, the latter as purposely synthesized endocrine disruptors, are explained to support this view. According to our present knowledge, there is no reason to suppose that such far-reaching changes are in any sense unique. The additional existing evidence for ED in invertebrates from laboratory and field studies are summarized as an update and amendment of the EDIETA report from 1998. Finally, conclusions about the scale and implications of the observed effects are drawn and further research needs are defined. © 2013 Walter de Gruyter GmbH, Berlin/Boston Oehlmann J. Department of Ecology and Evolution - Ecotoxicology, Johann Wolfgang Goethe University Frankfurt, D-60054, Frankfurt am Main, Germany aut Schulte-Oehlmann U. Department of Ecology and Evolution - Ecotoxicology, Johann Wolfgang Goethe University Frankfurt, D-60054, Frankfurt am Main, Germany aut Pure and Applied Chemistry De Gruyter 75/11-12(2003-01-01), 2207-2218 0033-4545 75:11-12<2207 2003 75 pac https://doi.org/10.1351/pac200375112207 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1351/pac200375112207 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Oehlmann J. Department of Ecology and Evolution - Ecotoxicology, Johann Wolfgang Goethe University Frankfurt, D-60054, Frankfurt am Main, Germany aut NATIONALLICENCE 700 1- Schulte-Oehlmann U. Department of Ecology and Evolution - Ecotoxicology, Johann Wolfgang Goethe University Frankfurt, D-60054, Frankfurt am Main, Germany aut NATIONALLICENCE 773 0- Pure and Applied Chemistry De Gruyter 75/11-12(2003-01-01), 2207-2218 0033-4545 75:11-12<2207 2003 75 pac CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter