Mevalonate-independent methylerythritol phosphate pathway for isoprenoid biosynthesis. Elucidation and distribution
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| 024 | 7 | 0 | |a 10.1351/pac200375020375 |2 doi |
| 035 | |a (NATIONALLICENCE)gruyter-10.1351/pac200375020375 | ||
| 100 | 1 | |a Rohmer |D M. |u Université Louis Pasteur/CNRS/Institut Universitaire de France, Institut Le Bel, 4 rue Blaise Pascal, 67070 Strasbourg Cedex, France | |
| 245 | 1 | 0 | |a Mevalonate-independent methylerythritol phosphate pathway for isoprenoid biosynthesis. Elucidation and distribution |h [Elektronische Daten] |c [M. Rohmer] |
| 520 | 3 | |a A long-overlooked metabolic pathway for isoprenoid biosynthesis, the mevalonate-independent methylerythritol phosphate (MEP) pathway, is present in many bacteria and in the chloroplasts of all phototrophic organisms. It represents an alternative to the well known mevalonate pathway, which is present in animals, fungi, plant cytoplasm, archaebacteria, and some eubacteria. This contribution summarizes key steps of its elucidation and the state-of-the-art knowledge of this biosynthetic pathway, which represents a novel target for antibacterial and antiparasitic drugs. | |
| 540 | |a © 2013 Walter de Gruyter GmbH, Berlin/Boston | ||
| 773 | 0 | |t Pure and Applied Chemistry |d De Gruyter |g 75/2-3(2003-01-01), 375-388 |x 0033-4545 |q 75:2-3<375 |1 2003 |2 75 |o pac | |
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1351/pac200375020375 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 100 |E 1- |a Rohmer |D M. |u Université Louis Pasteur/CNRS/Institut Universitaire de France, Institut Le Bel, 4 rue Blaise Pascal, 67070 Strasbourg Cedex, France | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Pure and Applied Chemistry |d De Gruyter |g 75/2-3(2003-01-01), 375-388 |x 0033-4545 |q 75:2-3<375 |1 2003 |2 75 |o pac | ||
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