caa a22 4500 378866249 CHVBK 20180305123358.0 cr unu---uuuuu 161128e20030101xx s 000 0 eng 10.1351/pac200375020343 doi (NATIONALLICENCE)gruyter-10.1351/pac200375020343 Detection of pharmacologically active natural products using ecology. Selected examples from Indopacific marine invertebrates and sponge-derived fungi [Elektronische Daten] [P. Proksch, R. Ebel, R. A. Edrada, P. Schupp, W. H. Lin, Sudarsono,, V. Wray, K. Steube] This review article presents our group's recent research findings with regard to bioactive natural products from marine sponges and tunicates, as well as from sponge derived fungi. The organisms discussed originate in the Indopacific region, which has an exceptionally rich marine biodiversity. Major topics that are covered in our review include the chemical ecology of sponges, focusing on defense against fishes, as well as the isolation and identification of new bioactive constituents from sponges and tunicates. Sponge derived fungi are introduced as an emerging source for new bioactive metabolites, reflecting the currently growing interest in natural products from marine microorganisms. © 2013 Walter de Gruyter GmbH, Berlin/Boston Proksch P. Institut für Pharmazeutische Biologie, Heinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1 Geb. 26.23, D-40225 Düsseldorf, Germany aut Ebel R. Centre for Marine Biofouling and Bio-Innovation, University of New South Wales, Sydney, 2052 Australia aut Edrada R. A. Institut für Pharmazeutische Biologie, Heinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1 Geb. 26.23, D-40225 Düsseldorf, Germany aut Schupp P. Centre for Marine Biofouling and Bio-Innovation, University of New South Wales, Sydney, 2052 Australia aut Lin W. H. National Research Laboratories of Natural and Biomimetic Drugs, Peking University, No. 8 Xueyang Road, 100083 Beijing, PR China aut Sudarsono, Centre for Traditional Medicine, Gadjah Mada University, Yogyakarta 55281, Indonesia aut Wray V. Gesellschaft für Biotechnologische Forschung mbH, Mascheroder Weg 1, D-38124 Braunschweig, Germany aut Steube K. DSMZ, Mascheroder Weg 1b, D-38124 Braunschweig, Germany aut Pure and Applied Chemistry De Gruyter 75/2-3(2003-01-01), 343-352 0033-4545 75:2-3<343 2003 75 pac https://doi.org/10.1351/pac200375020343 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1351/pac200375020343 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Proksch P. Institut für Pharmazeutische Biologie, Heinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1 Geb. 26.23, D-40225 Düsseldorf, Germany aut NATIONALLICENCE 700 1- Ebel R. Centre for Marine Biofouling and Bio-Innovation, University of New South Wales, Sydney, 2052 Australia aut NATIONALLICENCE 700 1- Edrada R. A. Institut für Pharmazeutische Biologie, Heinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1 Geb. 26.23, D-40225 Düsseldorf, Germany aut NATIONALLICENCE 700 1- Schupp P. Centre for Marine Biofouling and Bio-Innovation, University of New South Wales, Sydney, 2052 Australia aut NATIONALLICENCE 700 1- Lin W. H. National Research Laboratories of Natural and Biomimetic Drugs, Peking University, No. 8 Xueyang Road, 100083 Beijing, PR China aut NATIONALLICENCE 700 1- Sudarsono Centre for Traditional Medicine, Gadjah Mada University, Yogyakarta 55281, Indonesia aut NATIONALLICENCE 700 1- Wray V. Gesellschaft für Biotechnologische Forschung mbH, Mascheroder Weg 1, D-38124 Braunschweig, Germany aut NATIONALLICENCE 700 1- Steube K. DSMZ, Mascheroder Weg 1b, D-38124 Braunschweig, Germany aut NATIONALLICENCE 773 0- Pure and Applied Chemistry De Gruyter 75/2-3(2003-01-01), 343-352 0033-4545 75:2-3<343 2003 75 pac CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter