caa a22 4500 378866257 CHVBK 20180305123358.0 cr unu---uuuuu 161128e20030101xx s 000 0 eng 10.1351/pac200375020389 doi (NATIONALLICENCE)gruyter-10.1351/pac200375020389 Biotransformation of triptonide by cell suspension cultures of Platycodon grandiflorum [Elektronische Daten] [L. Ning, Hongzhu Guo, Xiaomei Jiang, Kaishun Bi, Dean Guo] The biotransformation of triptonide by cell suspension cultures of Platycodon grandiflorum was investigated. After six days of incubation, five products were obtained. On the basis of chemical and spectral evidence, their structures were elucidated as epitriptolide-14-O-β-d-glucoside, 5α-hydroxytriptonide, triptolide, triptodiolide, and 2β-hydroxytriptonide, among which epitriptolide-14-O-β-d-glucoside and 5α-hydroxytriptonide are new compounds. © 2013 Walter de Gruyter GmbH, Berlin/Boston Ning L. Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China aut Guo Hongzhu The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100083, P. R. China aut Jiang Xiaomei The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100083, P. R. China aut Bi Kaishun Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China aut Guo Dean The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100083, P. R. China aut Pure and Applied Chemistry De Gruyter 75/2-3(2003-01-01), 389-393 0033-4545 75:2-3<389 2003 75 pac https://doi.org/10.1351/pac200375020389 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1351/pac200375020389 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ning L. Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China aut NATIONALLICENCE 700 1- Guo Hongzhu The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100083, P. R. China aut NATIONALLICENCE 700 1- Jiang Xiaomei The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100083, P. R. China aut NATIONALLICENCE 700 1- Bi Kaishun Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China aut NATIONALLICENCE 700 1- Guo Dean The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100083, P. R. China aut NATIONALLICENCE 773 0- Pure and Applied Chemistry De Gruyter 75/2-3(2003-01-01), 389-393 0033-4545 75:2-3<389 2003 75 pac CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter