caa a22 4500 378867296 CHVBK 20180305123401.0 cr unu---uuuuu 161128e20030617xx s 000 0 eng 10.1515/CCLM.2003.114 doi (NATIONALLICENCE)gruyter-10.1515/CCLM.2003.114 Capillary Electrophoresis of Hemoglobin [Elektronische Daten] [Margaret Jenkins, Sujiva Ratnaike] Capillary electrophoresis (CE) has been used in a variety of in-house capillary isoelectric focusing (CIEF) and capillary zone electrophoresis (CZE) assays for the detection of hemoglobin (Hb) variants and the quantitation of HbA2 and HbF. A commercial kit has also been produced for the analysis of hemoglobin variants and thalassemia screening. Though CE methods have been shown to be able to detect many variants, final identification of the variant needs specialized testing such as DNA technology. Over the past 2 years, many instruments that had been used for these hemoglobin variant screening and thalassemia assays have been withdrawn from sale. Although CE HbA1c analysis is available, it cannot compete in turnaround time or cost with automated HPLC commercial instruments that give accurate HbA1c results in 3 or 4 minutes. Hence we do not anticipate a bright future for the analysis of hemoglobin by CE. Copyright © 2003 by Walter de Gruyter GmbH & Co. KG Medical equipment & techniques nationallicence Medical diagnosis nationallicence Diseases & disorders nationallicence Jenkins Margaret aut Ratnaike Sujiva aut Clinical Chemistry and Laboratory Medicine Walter de Gruyter 41/6(2003-06-17), 747-754 1434-6621 41:6<747 2003 41 cclm https://doi.org/10.1515/CCLM.2003.114 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1515/CCLM.2003.114 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Jenkins Margaret aut NATIONALLICENCE 700 1- Ratnaike Sujiva aut NATIONALLICENCE 773 0- Clinical Chemistry and Laboratory Medicine Walter de Gruyter 41/6(2003-06-17), 747-754 1434-6621 41:6<747 2003 41 cclm CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter