Requirements for Reproducibility, Truenessand Error of Measurement in Internal QualityControl Schemes

Verfasser / Beitragende:
[Piero Bonvicini, Paolo Metus, Maria A. Pavón, Massimo Tocchini]
Ort, Verlag, Jahr:
2003
Enthalten in:
Clinical Chemistry and Laboratory Medicine, 41/5(2003-05-15), 693-699
Format:
Artikel (online)
ID: 378876023
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024 7 0 |a 10.1515/CCLM.2003.105  |2 doi 
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245 0 0 |a Requirements for Reproducibility, Truenessand Error of Measurement in Internal QualityControl Schemes  |h [Elektronische Daten]  |c [Piero Bonvicini, Paolo Metus, Maria A. Pavón, Massimo Tocchini] 
520 3 |a Among the various models proposed to meet requirements for metrological performance in clinical laboratory measurements, that most widely used is intraand inter-biological variation. However, this model has weaknesses: a) in some cases, intra-individual biological variation is so small that requirements based on such data may not be met by routine methods; b) there is great variation among the intra- and inter-individual biological variations themselves. We therefore propose integration between "state-of-the-art” methods to minimize imprecision, and also suggest that requirements calculated on the basis of biological variations should be used in setting requirements for minimizing imprecision. Furthermore, we describe a new scale for setting requirements from biological variation data and suggest that systematic error should be corrected whenever it is statistically significant. 
540 |a Copyright © 2003 by Walter de Gruyter GmbH & Co. KG 
690 7 |a Medical equipment & techniques  |2 nationallicence 
690 7 |a Medical diagnosis  |2 nationallicence 
690 7 |a Diseases & disorders  |2 nationallicence 
700 1 |a Bonvicini  |D Piero  |4 aut 
700 1 |a Metus  |D Paolo  |4 aut 
700 1 |a Pavón  |D Maria A.  |4 aut 
700 1 |a Tocchini  |D Massimo  |4 aut 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Pavón  |D Maria A.  |4 aut 
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