caa a22 4500 378879227 CHVBK 20180305123428.0 cr unu---uuuuu 161128e20030721xx s 000 0 eng 10.1515/CCLM.2003.145 doi (NATIONALLICENCE)gruyter-10.1515/CCLM.2003.145 Problems of Comparing Blood Glucose Molality and Molarity Determined with an Omni, anEML 105 and an Ebio Analyser [Elektronische Daten] [Rainer Haeckel, Petra Hänecke] The comparability between glucose concentrations measured in various sample systems is still a matter of debate. Decision limits are usually determined in venous plasma and then converted to either blood or to the aqueous compartment (activity). The conversion factors recommended have not yet been generally accepted. In the present study, glucose concentrations were determined in blood and plasma with an Ebio analyzer (molarity) and in the aqueous compartment with both an EML 105 and an Omni (molality). All analytical results were referred to the same aqueous standard solution. The Ebio results agreed with reference method values in control materials. Concentrations determined in the various sample systems from patients (molarity) correlated well with the molality values measured either with the EML or the Omni. However, the mean values of the EML were not consistent with those derived theoretically by considering the different water content. With the Omni, only molality values in whole blood appeared plausible, but not in plasma, although the two sample systems should provide identical molality values. The EML results were almost identical in whole blood and plasma. Theoretically, glucose molality would be the ideal diagnostic quantity. However, no diagnostic advantage of molality determined in whole blood with the Omni vs. molarity values could be detected in a group of 40 non-diabetic and 27 diabetic subjects. Copyright © 2003 by Walter de Gruyter GmbH & Co. KG Medical equipment & techniques nationallicence Medical diagnosis nationallicence Diseases & disorders nationallicence Haeckel Rainer aut Hänecke Petra aut Clinical Chemistry and Laboratory Medicine Walter de Gruyter 41/7(2003-07-21), 950-957 1434-6621 41:7<950 2003 41 cclm https://doi.org/10.1515/CCLM.2003.145 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1515/CCLM.2003.145 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Haeckel Rainer aut NATIONALLICENCE 700 1- Hänecke Petra aut NATIONALLICENCE 773 0- Clinical Chemistry and Laboratory Medicine Walter de Gruyter 41/7(2003-07-21), 950-957 1434-6621 41:7<950 2003 41 cclm CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter