caa a22 4500 378880969 CHVBK 20180305123431.0 cr unu---uuuuu 161128e20030514xx s 000 0 eng 10.1515/JPM.2003.034 doi (NATIONALLICENCE)gruyter-10.1515/JPM.2003.034 Maternal smoking during pregnancy and appetite control in offspring [Elektronische Daten] [A. M. Toschke, Anna G. C. Ehlin, R. von Kries, A. Ekbom, S. M. Montgomery] Aims: Intrauterine exposure to tobacco smoke products has been associated with longterm neurobehavioral effects. Modified appetite control might explain the recently observed association between maternal smoking during pregnancy and obesity in offspring. Methods: Some 10,557 British adults aged 42 years born between 3-9 March 1958 were followed up in a birth cohort study (NCDS). The main outcome measure was selfreported poor appetite at age 42 years and main exposure was maternal smoking during pregnancy. Results: The proportion of offspring with poor appetite increased with maternal smoking during pregnancy:nonsmoking 4.5%; (4.0%-5.0%), medium smoking 5.6%; (4.5%-6.8%), variable smoking 6.8%; (4.9%-9.1%) and heavy smoking 7.7%; (6.3%-9.4%). The unadjusted odds ratios for maternal smoking during pregnancy (ever/never) and poor appetite is 1.49 (1.25-1.77) and after adjustment for BMI at 42 years and other potential confounding factors it is 1.22 (1.01-1.48). Conclusions: Offspring of mothers who smoked during pregnancy were more likely to report a poor appetite independent of a number of potential confounding factors. Although not in the expected direction, the results suggest maternal smoking during pregnancy may influence appetite perception through a developmental influence or through confounding by social factors. Copyright © 2003 by Walter de Gruyter GmbH & Co. KG Human reproduction, growth & development nationallicence Gynaecology & obstetrics nationallicence Paediatric medicine nationallicence Toschke A. M. aut Ehlin Anna G. C. aut von Kries R. aut Ekbom A. aut Montgomery S. M. aut Journal of Perinatal Medicine Walter de Gruyter 31/3(2003-05-14), 251-256 0300-5577 31:3<251 2003 31 jpme https://doi.org/10.1515/JPM.2003.034 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1515/JPM.2003.034 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Toschke A. M. aut NATIONALLICENCE 700 1- Ehlin Anna G. C. aut NATIONALLICENCE 700 1- von Kries R. aut NATIONALLICENCE 700 1- Ekbom A. aut NATIONALLICENCE 700 1- Montgomery S. M. aut NATIONALLICENCE 773 0- Journal of Perinatal Medicine Walter de Gruyter 31/3(2003-05-14), 251-256 0300-5577 31:3<251 2003 31 jpme CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter