The HELLP-syndrome; maternal-fetal outcome and follow up of infants

Verfasser / Beitragende:
[A. C. Roelofsen, M. G. van Pampus, J. G. Aarnoudse]
Ort, Verlag, Jahr:
2003
Enthalten in:
Journal of Perinatal Medicine, 31/3(2003-05-14), 201-208
Format:
Artikel (online)
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024 7 0 |a 10.1515/JPM.2003.027  |2 doi 
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245 0 4 |a The HELLP-syndrome; maternal-fetal outcome and follow up of infants  |h [Elektronische Daten]  |c [A. C. Roelofsen, M. G. van Pampus, J. G. Aarnoudse] 
520 3 |a Objective: To investigate maternal-fetal outcome of infants born after pregnancies complicated by (H)ELLP syndrome. Study design: A retrospective cohort study was performed on patients with the HELLP or ELLP syndrome. Maternal and perinatal complications were recorded. The follow-up period of the infants was at least 18 months. A multivariate regression analysis was done to define the variables mostly contributing to adverse outcome. Results: No maternal deaths occurred. Eighteen infants of the HELLP group and six infants of the ELLP group died; total perinatal mortality was 17.6%. After 18 months four infants had major handicaps, making a total adverse outcome of 22.8%. Statistical analysis shows early gestational age, prolongation of pregnancy and administration of antihypertensive medication as the factors influencing outcome of the infants most. Conclusions: Prolongation of pregnancy contributed to better perinatal outcome, while administration of antihypertensive medication and early gestational age were related to a more unfavorable outcome. 
540 |a Copyright © 2003 by Walter de Gruyter GmbH & Co. KG 
690 7 |a Human reproduction, growth & development  |2 nationallicence 
690 7 |a Gynaecology & obstetrics  |2 nationallicence 
690 7 |a Paediatric medicine  |2 nationallicence 
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700 1 |a van Pampus  |D M. G.  |4 aut 
700 1 |a Aarnoudse  |D J. G.  |4 aut 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Aarnoudse  |D J. G.  |4 aut 
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