caa a22 4500 378881035 CHVBK 20180305123431.0 cr unu---uuuuu 161128e20030514xx s 000 0 eng 10.1515/JPM.2003.027 doi (NATIONALLICENCE)gruyter-10.1515/JPM.2003.027 The HELLP-syndrome; maternal-fetal outcome and follow up of infants [Elektronische Daten] [A. C. Roelofsen, M. G. van Pampus, J. G. Aarnoudse] Objective: To investigate maternal-fetal outcome of infants born after pregnancies complicated by (H)ELLP syndrome. Study design: A retrospective cohort study was performed on patients with the HELLP or ELLP syndrome. Maternal and perinatal complications were recorded. The follow-up period of the infants was at least 18 months. A multivariate regression analysis was done to define the variables mostly contributing to adverse outcome. Results: No maternal deaths occurred. Eighteen infants of the HELLP group and six infants of the ELLP group died; total perinatal mortality was 17.6%. After 18 months four infants had major handicaps, making a total adverse outcome of 22.8%. Statistical analysis shows early gestational age, prolongation of pregnancy and administration of antihypertensive medication as the factors influencing outcome of the infants most. Conclusions: Prolongation of pregnancy contributed to better perinatal outcome, while administration of antihypertensive medication and early gestational age were related to a more unfavorable outcome. Copyright © 2003 by Walter de Gruyter GmbH & Co. KG Human reproduction, growth & development nationallicence Gynaecology & obstetrics nationallicence Paediatric medicine nationallicence Roelofsen A. C. aut van Pampus M. G. aut Aarnoudse J. G. aut Journal of Perinatal Medicine Walter de Gruyter 31/3(2003-05-14), 201-208 0300-5577 31:3<201 2003 31 jpme https://doi.org/10.1515/JPM.2003.027 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1515/JPM.2003.027 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Roelofsen A. C. aut NATIONALLICENCE 700 1- van Pampus M. G. aut NATIONALLICENCE 700 1- Aarnoudse J. G. aut NATIONALLICENCE 773 0- Journal of Perinatal Medicine Walter de Gruyter 31/3(2003-05-14), 201-208 0300-5577 31:3<201 2003 31 jpme CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter