caa a22 4500 378881426 CHVBK 20180305123432.0 cr unu---uuuuu 161128e20030807xx s 000 0 eng 10.1515/CCLM.2003.156 doi (NATIONALLICENCE)gruyter-10.1515/CCLM.2003.156 Trace Elements, Innate Immune Response and Parasites [Elektronische Daten] [Maria Teresa Rivera, Andrea Pereira De Souza, Tania Cremonini Araujo-Jorge, Solange Lisboa De Castro, Jean Vanderpas] Micronutrient deficiencies and infectious disease often coexist and show complex interactions leading to mutually reinforced detrimental clinical effects. Such a combination is predominantly observed in underprivileged people of developing countries, particularly in rural regions. Several micronutrients such as trace elements (zinc, iron, selenium) modulate immune function and influence the susceptibility of the host to infection. Nevertheless, the effect of individual micronutrients on components of innate immunity is difficult to design and interpret. Micronutrient deficiency, in general, has a widespread effect on nearly all components of the innate immune response. Chagas' disease is a pertinent model to study interaction of nutrition, immunity and infection, as it implies many components of innate immunity. An important question is whether alterations on micronutrient intake modify the course of infection. Some interactions of trace elements with innate immunity and acute inflammatory response are reviewed in this article with a special focus on selenium deficiency and Trypanosoma cruzi infection Copyright © 2003 by Walter de Gruyter GmbH & Co. KG Medical equipment & techniques nationallicence Medical diagnosis nationallicence Diseases & disorders nationallicence Rivera Maria Teresa aut Souza Andrea Pereira De aut Araujo-Jorge Tania Cremonini aut De Castro Solange Lisboa aut Vanderpas Jean aut Clinical Chemistry and Laboratory Medicine Walter de Gruyter 41/8(2003-08-07), 1020-1025 1434-6621 41:8<1020 2003 41 cclm https://doi.org/10.1515/CCLM.2003.156 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1515/CCLM.2003.156 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Rivera Maria Teresa aut NATIONALLICENCE 700 1- Souza Andrea Pereira De aut NATIONALLICENCE 700 1- Araujo-Jorge Tania Cremonini aut NATIONALLICENCE 700 1- De Castro Solange Lisboa aut NATIONALLICENCE 700 1- Vanderpas Jean aut NATIONALLICENCE 773 0- Clinical Chemistry and Laboratory Medicine Walter de Gruyter 41/8(2003-08-07), 1020-1025 1434-6621 41:8<1020 2003 41 cclm CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter