The Effect of Selenium on Immune Functions of J774.1 Cells
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| 024 | 7 | 0 | |a 10.1515/CCLM.2003.154 |2 doi |
| 035 | |a (NATIONALLICENCE)gruyter-10.1515/CCLM.2003.154 | ||
| 245 | 0 | 4 | |a The Effect of Selenium on Immune Functions of J774.1 Cells |h [Elektronische Daten] |c [Nadia Safir, Albrecht Wendel, Rachid Saile, Layachi Chabraoui] |
| 520 | 3 | |a The J774.1 macrophage cell line was used as a tool to investigate the influence of selenium on macrophage function. In vitro selenium supplementation enhanced phagocytosis, degranulation by the release of β-glucuronidase after N-formyl-methionyl-leucyl-phenylalanine (FMLP) or cytochalasin B, and the production of superoxide anion after phorbol myristate acetate stimulation of these cells, while the release of nitric oxide was not affected by the selenium status. Selenium supplementation enhanced significantly (p < 0.05) the release of tumor necrosis factor (5-fold), interleukin-1 (3-fold) and interleukin-6 (2.5-fold) after 10 μg/ml lipopolysaccharide stimulation compared to selenium-deficient cells. | |
| 540 | |a Copyright (c) 2003 by Walter de Gruyter GmbH & Co. KG | ||
| 690 | 7 | |a Medical equipment & techniques |2 nationallicence | |
| 690 | 7 | |a Medical diagnosis |2 nationallicence | |
| 690 | 7 | |a Diseases & disorders |2 nationallicence | |
| 700 | 1 | |a Safir |D Nadia |4 aut | |
| 700 | 1 | |a Wendel |D Albrecht |4 aut | |
| 700 | 1 | |a Saile |D Rachid |4 aut | |
| 700 | 1 | |a Chabraoui |D Layachi |4 aut | |
| 773 | 0 | |t Clinical Chemistry and Laboratory Medicine |d Walter de Gruyter |g 41/8(2003-08-07), 1005-1011 |x 1434-6621 |q 41:8<1005 |1 2003 |2 41 |o cclm | |
| 856 | 4 | 0 | |u https://doi.org/10.1515/CCLM.2003.154 |q text/html |z Onlinezugriff via DOI |
| 908 | |D 1 |a research article |2 jats | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1515/CCLM.2003.154 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Safir |D Nadia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Wendel |D Albrecht |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Saile |D Rachid |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Chabraoui |D Layachi |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Clinical Chemistry and Laboratory Medicine |d Walter de Gruyter |g 41/8(2003-08-07), 1005-1011 |x 1434-6621 |q 41:8<1005 |1 2003 |2 41 |o cclm | ||
| 900 | 7 | |b CC0 |u http://creativecommons.org/publicdomain/zero/1.0 |2 nationallicence | |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-gruyter | ||