caa a22 4500 378882686 CHVBK 20180305123435.0 cr unu---uuuuu 161128e20041104xx s 000 0 eng 10.1515/JPM.2004.122 doi (NATIONALLICENCE)gruyter-10.1515/JPM.2004.122 Strategy for management of newborns with cervical teratoma [Elektronische Daten] [Antoine De Backer, Gerard C. Madern, Cees P. van De Ven, Dick Tibboel, Frans W.J. Hazebroek] Background: Cervical teratomas are extremely rare tumors with high perinatal mortality and morbidity rates. Objective: To compare our experience and outcome in newborns with cervical teratoma with similar reports from the literature, in order to propose a structured approach. Methods: A retrospective review of seven patients treated between 1986 and 2000 was performed. The results of these seven patients were compared with and added to a series of 44 well-documented patients retrieved from the literature. Results: In four of the seven patients, the diagnosis was not suspected antenatally. Three of the patients survived, one died. In the other three, the diagnosis was made antenatally. Two were born using the ex-utero intrapartum treatment (EXIT) procedure, one by planned cesarean section. Only one of these three survived. Mortality in the total series of 51 patients was 33% overall, and 46% in the group in which the diagnosis had been made antenatally. Peri- and post-operative complications were reported in 27%. Although larger tumors caused polyhydramnios more frequently than smaller tumors, and were associated with more severe respiratory distress, the relationship between tumor volume at birth and final outcome could not be established. This makes difficult the identification of fetuses with a disastrous prognosis. Conclusion: Although mostly benign, cervical teratomas are still associated with high mortality rates. Timely antenatal diagnosis is indispensable in reducing morbidity and mortality caused by upper airway obstruction. A structured approach to the management of cervical teratoma is proposed. © Walter de Gruyter Human reproduction, growth & development nationallicence Gynaecology & obstetrics nationallicence Paediatric medicine nationallicence ex-utero intrapartum treatment (EXIT) procedure nationallicence germ cell tumor nationallicence neck mass (fetal, neonatal) nationallicence prenatal diagnosis nationallicence teratoma (neck, cervical) nationallicence De Backer Antoine Academic Hospital, Free University of Brussels, Brussels, Belgium aut Madern Gerard C. Departments of Pediatric Surgery, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands aut van De Ven Cees P. Departments of Pediatric Surgery, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands aut Tibboel Dick Departments of Pediatric Surgery, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands aut Hazebroek Frans W.J. Departments of Pediatric Surgery, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands aut Journal of Perinatal Medicine Walter de Gruyter 32/6(2004-11-04), 500-508 0300-5577 32:6<500 2004 32 jpme https://doi.org/10.1515/JPM.2004.122 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1515/JPM.2004.122 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- De Backer Antoine Academic Hospital, Free University of Brussels, Brussels, Belgium aut NATIONALLICENCE 700 1- Madern Gerard C. Departments of Pediatric Surgery, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- van De Ven Cees P. Departments of Pediatric Surgery, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- Tibboel Dick Departments of Pediatric Surgery, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- Hazebroek Frans W.J. Departments of Pediatric Surgery, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands aut NATIONALLICENCE 773 0- Journal of Perinatal Medicine Walter de Gruyter 32/6(2004-11-04), 500-508 0300-5577 32:6<500 2004 32 jpme CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter