Expression analysis of BCL2L12, a new member of apoptosis-related genes, in colon cancer
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| 024 | 7 | 0 | |a 10.1515/BC.2004.101 |2 doi |
| 035 | |a (NATIONALLICENCE)gruyter-10.1515/BC.2004.101 | ||
| 245 | 0 | 0 | |a Expression analysis of BCL2L12, a new member of apoptosis-related genes, in colon cancer |h [Elektronische Daten] |c [Konstantina Mathioudaki, Andreas Scorilas, Alexandra Papadokostopoulou, Dimitrios Xynopoulos, Niki Arnogianaki, Niki Agnanti, Maroulio Talieri] |
| 520 | 3 | |a Apoptosis is an active process regulated by a variety of genes. Recently, the molecular cloning, physical mapping and expression analysis of a novel gene of the Bcl-2 family, BCL2L12, was reported. Expression analysis of the BCL2L12 gene in breast cancer confirmed an association of BCL2L12 with favorable prognosis of patients. In the present study, the expression of the BCL2L12 gene was analyzed in colon cancer by RT-PCR. Two transcripts, BCL2L12 and BCL2L12-A, were overexpressed in the cancer tissues as compared to their paired normal mucosa. An association was found between BCL2L12-A transcript expression and nodal status, as well as Dukes' stage. The BCL2L12-A transcript appears to be of importance for colon cancer since its expression is associated with disease progression. | |
| 540 | |a © Walter de Gruyter | ||
| 690 | 7 | |a Biochemistry |2 nationallicence | |
| 690 | 7 | |a Molecular biology |2 nationallicence | |
| 690 | 7 | |a Cellular biology |2 nationallicence | |
| 690 | 7 | |a apoptosis |2 nationallicence | |
| 690 | 7 | |a BCL2L12 |2 nationallicence | |
| 690 | 7 | |a colon cancer |2 nationallicence | |
| 700 | 1 | |a Mathioudaki |D Konstantina |u G. Papanicolaou Research Center of Oncology, ‘Saint Savas' Hospital, GR-11522 Athens, Greece |4 aut | |
| 700 | 1 | |a Scorilas |D Andreas |u Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Athens GR-15711 Athens, Greece |4 aut | |
| 700 | 1 | |a Papadokostopoulou |D Alexandra |u Department of Gastroenterology, ‘Saint Savas' Hospital, GR-11522 Athens, Greece |4 aut | |
| 700 | 1 | |a Xynopoulos |D Dimitrios |u Department of Gastroenterology, ‘Saint Savas' Hospital, GR-11522 Athens, Greece |4 aut | |
| 700 | 1 | |a Arnogianaki |D Niki |u Department of Pathology, ‘Saint Savas' Hospital, GR-11522 Athens, Greece |4 aut | |
| 700 | 1 | |a Agnanti |D Niki |u Department of Pathology, Medical School, University of Ioannina, GR-45110, Greece |4 aut | |
| 700 | 1 | |a Talieri |D Maroulio |u G. Papanicolaou Research Center of Oncology, ‘Saint Savas' Hospital, GR-11522 Athens, Greece |4 aut | |
| 773 | 0 | |t Biological Chemistry |d Walter de Gruyter |g 385/9(2004-09-01), 779-783 |x 1431-6730 |q 385:9<779 |1 2004 |2 385 |o bchm | |
| 856 | 4 | 0 | |u https://doi.org/10.1515/BC.2004.101 |q text/html |z Onlinezugriff via DOI |
| 908 | |D 1 |a research article |2 jats | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1515/BC.2004.101 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Mathioudaki |D Konstantina |u G. Papanicolaou Research Center of Oncology, ‘Saint Savas' Hospital, GR-11522 Athens, Greece |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Scorilas |D Andreas |u Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Athens GR-15711 Athens, Greece |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Papadokostopoulou |D Alexandra |u Department of Gastroenterology, ‘Saint Savas' Hospital, GR-11522 Athens, Greece |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Xynopoulos |D Dimitrios |u Department of Gastroenterology, ‘Saint Savas' Hospital, GR-11522 Athens, Greece |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Arnogianaki |D Niki |u Department of Pathology, ‘Saint Savas' Hospital, GR-11522 Athens, Greece |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Agnanti |D Niki |u Department of Pathology, Medical School, University of Ioannina, GR-45110, Greece |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Talieri |D Maroulio |u G. Papanicolaou Research Center of Oncology, ‘Saint Savas' Hospital, GR-11522 Athens, Greece |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Biological Chemistry |d Walter de Gruyter |g 385/9(2004-09-01), 779-783 |x 1431-6730 |q 385:9<779 |1 2004 |2 385 |o bchm | ||
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