Emergency department triage of patients with acute chest pain: definition of cardiac troponin I decisional value to manage patients without electrocardiographic evidence of ischemia
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| 024 | 7 | 0 | |a 10.1515/CCLM.2004.094 |2 doi |
| 035 | |a (NATIONALLICENCE)gruyter-10.1515/CCLM.2004.094 | ||
| 245 | 0 | 0 | |a Emergency department triage of patients with acute chest pain: definition of cardiac troponin I decisional value to manage patients without electrocardiographic evidence of ischemia |h [Elektronische Daten] |c [Pascale Beyne, Erik Bouvier, Patrick Werner, Pierre Bourgoin, Damien Logeart, Laurent Alliot, Habiba Daïkha, Michel Vidaud] |
| 520 | 3 | |a The aim of this study was to define the use of a new cardiac troponin I (cTnI) assay for emergency patients with chest pain and no specific electrocardiographic changes consistent with the presence of ischemia. Patients (n=106) admitted in Emergency/Cardiology Departments for chest pain and suspicion of acute coronary syndrome (ACS) were randomized into two diagnosis groups (ACS or non-ACS) by two independent cardiologists. cTnI measurements were performed at admission, and 6 hours and 12 hours later with a new generation assay (Access AccuTnI, Beckman Coulter). Using an upper reference limit of 0.04 μg/l, 27 patients had a cTnI elevation not related to the final diagnosis of ischemia; the positive predictive value (PPV) was 67% with specificity 48%. The decisional value was re-defined and set at 0.16 μg/l, a concentration corresponding to the 99th percentile of the non-ACS patient group. Precision (coefficient of variation) was 8% at this level, PPV 97% and specificity 98%. This new decisional value is now used in our institution and could be included in standard care guidelines to improve the management of patients presenting chest pain in emergency departments. | |
| 540 | |a Copyright © 2004 by Walter de Gruyter GmbH & Co. KG | ||
| 690 | 7 | |a Medical equipment & techniques |2 nationallicence | |
| 690 | 7 | |a Medical diagnosis |2 nationallicence | |
| 690 | 7 | |a Diseases & disorders |2 nationallicence | |
| 700 | 1 | |a Beyne |D Pascale |4 aut | |
| 700 | 1 | |a Bouvier |D Erik |4 aut | |
| 700 | 1 | |a Werner |D Patrick |4 aut | |
| 700 | 1 | |a Bourgoin |D Pierre |4 aut | |
| 700 | 1 | |a Logeart |D Damien |4 aut | |
| 700 | 1 | |a Alliot |D Laurent |4 aut | |
| 700 | 1 | |a Daïkha |D Habiba |4 aut | |
| 700 | 1 | |a Vidaud |D Michel |4 aut | |
| 773 | 0 | |t Clinical Chemistry and Laboratory Medicine |d Walter de Gruyter |g 42/5(2004-05-10), 556-559 |x 1434-6621 |q 42:5<556 |1 2004 |2 42 |o cclm | |
| 856 | 4 | 0 | |u https://doi.org/10.1515/CCLM.2004.094 |q text/html |z Onlinezugriff via DOI |
| 908 | |D 1 |a research article |2 jats | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1515/CCLM.2004.094 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Beyne |D Pascale |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Bouvier |D Erik |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Werner |D Patrick |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Bourgoin |D Pierre |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Logeart |D Damien |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Alliot |D Laurent |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Daïkha |D Habiba |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Vidaud |D Michel |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Clinical Chemistry and Laboratory Medicine |d Walter de Gruyter |g 42/5(2004-05-10), 556-559 |x 1434-6621 |q 42:5<556 |1 2004 |2 42 |o cclm | ||
| 900 | 7 | |b CC0 |u http://creativecommons.org/publicdomain/zero/1.0 |2 nationallicence | |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-gruyter | ||