caa a22 4500 378892150 CHVBK 20180305123457.0 cr unu---uuuuu 161128e20040510xx s 000 0 eng 10.1515/CCLM.2004.094 doi (NATIONALLICENCE)gruyter-10.1515/CCLM.2004.094 Emergency department triage of patients with acute chest pain: definition of cardiac troponin I decisional value to manage patients without electrocardiographic evidence of ischemia [Elektronische Daten] [Pascale Beyne, Erik Bouvier, Patrick Werner, Pierre Bourgoin, Damien Logeart, Laurent Alliot, Habiba Daïkha, Michel Vidaud] The aim of this study was to define the use of a new cardiac troponin I (cTnI) assay for emergency patients with chest pain and no specific electrocardiographic changes consistent with the presence of ischemia. Patients (n=106) admitted in Emergency/Cardiology Departments for chest pain and suspicion of acute coronary syndrome (ACS) were randomized into two diagnosis groups (ACS or non-ACS) by two independent cardiologists. cTnI measurements were performed at admission, and 6 hours and 12 hours later with a new generation assay (Access AccuTnI, Beckman Coulter). Using an upper reference limit of 0.04 μg/l, 27 patients had a cTnI elevation not related to the final diagnosis of ischemia; the positive predictive value (PPV) was 67% with specificity 48%. The decisional value was re-defined and set at 0.16 μg/l, a concentration corresponding to the 99th percentile of the non-ACS patient group. Precision (coefficient of variation) was 8% at this level, PPV 97% and specificity 98%. This new decisional value is now used in our institution and could be included in standard care guidelines to improve the management of patients presenting chest pain in emergency departments. Copyright © 2004 by Walter de Gruyter GmbH & Co. KG Medical equipment & techniques nationallicence Medical diagnosis nationallicence Diseases & disorders nationallicence Beyne Pascale aut Bouvier Erik aut Werner Patrick aut Bourgoin Pierre aut Logeart Damien aut Alliot Laurent aut Daïkha Habiba aut Vidaud Michel aut Clinical Chemistry and Laboratory Medicine Walter de Gruyter 42/5(2004-05-10), 556-559 1434-6621 42:5<556 2004 42 cclm https://doi.org/10.1515/CCLM.2004.094 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1515/CCLM.2004.094 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Beyne Pascale aut NATIONALLICENCE 700 1- Bouvier Erik aut NATIONALLICENCE 700 1- Werner Patrick aut NATIONALLICENCE 700 1- Bourgoin Pierre aut NATIONALLICENCE 700 1- Logeart Damien aut NATIONALLICENCE 700 1- Alliot Laurent aut NATIONALLICENCE 700 1- Daïkha Habiba aut NATIONALLICENCE 700 1- Vidaud Michel aut NATIONALLICENCE 773 0- Clinical Chemistry and Laboratory Medicine Walter de Gruyter 42/5(2004-05-10), 556-559 1434-6621 42:5<556 2004 42 cclm CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter