caa a22 4500 378892215 CHVBK 20180305123457.0 cr unu---uuuuu 161128e20040510xx s 000 0 eng 10.1515/CCLM.2004.081 doi (NATIONALLICENCE)gruyter-10.1515/CCLM.2004.081 Beyond cholesterol - inflammatory cytokines, the key mediators in atherosclerosis [Elektronische Daten] [Harald Mangge, Holger Hubmann, Stefan Pilz, Konrad Schauenstein, Wilfried Renner, Winfried März] The development of atherosclerotic lesions encompasses a cascade of cellular and molecular responses that can at best be characterized as an inflammatory process, and exhibits striking similarities to autoimmune diseases, such as rheumatoid arthritis. Chemokines, cytokines and their receptors are critically involved in initiation and perpetuation of atherosclerosis, and they play important roles at all levels in the pathogenesis of this disease. In the present article, the currently available information on cytokines and chemokines as key mediators in atherosclerosis is reviewed. Furthermore, based on recent experiences of our own with very early stages of atherosclerosis, possible new ways to make use of these parameters toward improved early detection, prevention and treatment of this disease are indicated. Copyright © 2004 by Walter de Gruyter GmbH & Co. KG Medical equipment & techniques nationallicence Medical diagnosis nationallicence Diseases & disorders nationallicence Mangge Harald aut Hubmann Holger aut Pilz Stefan aut Schauenstein Konrad aut Renner Wilfried aut März Winfried aut Clinical Chemistry and Laboratory Medicine Walter de Gruyter 42/5(2004-05-10), 467-474 1434-6621 42:5<467 2004 42 cclm https://doi.org/10.1515/CCLM.2004.081 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1515/CCLM.2004.081 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Mangge Harald aut NATIONALLICENCE 700 1- Hubmann Holger aut NATIONALLICENCE 700 1- Pilz Stefan aut NATIONALLICENCE 700 1- Schauenstein Konrad aut NATIONALLICENCE 700 1- Renner Wilfried aut NATIONALLICENCE 700 1- März Winfried aut NATIONALLICENCE 773 0- Clinical Chemistry and Laboratory Medicine Walter de Gruyter 42/5(2004-05-10), 467-474 1434-6621 42:5<467 2004 42 cclm CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter