Nanoporous thin films and porous inorganic substrates for lipid bilayer support materials

Verfasser / Beitragende:
[Shenda M. Baker, W. Stephen Kolthammer, Johannes B. Tan, Gregory S. Smith]
Ort, Verlag, Jahr:
2004
Enthalten in:
Zeitschrift für Kristallographie - Crystalline Materials, 219/3(2004-03-01), 179-185
Format:
Artikel (online)
ID: 378892967
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024 7 0 |a 10.1524/zkri.219.3.179.29090  |2 doi 
035 |a (NATIONALLICENCE)gruyter-10.1524/zkri.219.3.179.29090 
245 0 0 |a Nanoporous thin films and porous inorganic substrates for lipid bilayer support materials  |h [Elektronische Daten]  |c [Shenda M. Baker, W. Stephen Kolthammer, Johannes B. Tan, Gregory S. Smith] 
520 3 |a Synthetic lipid bilayers are excellent mimics of cell membranes. In order to experimentally access these thin layers and oriented proteins in membranes, suitable supports which allow for membrane fluidity while assuring membrane stability need to be developed. Nanoporous polymer templates created from the natural phase segregation of immiscible diblock copolymers are uniform arrays with pore sizes naturally on the scale of macromolecules, tens of nanometers, and grain sizes currently on the order of microns. We study the suitability of such templates, appropriately treated to present a hydrophilic surface, as substrates for lipid bilayers with scanning force microscopy and neutron reflectometry. In the process, we use tip deflection curves to establish simple criteria for determining the presence of a lipid layer on the substrates. Gold coated porous polymers and silicon oxide templates in silicon both appear to be suitable support materials. 
540 |a © 2004 Oldenbourg Wissenschaftsverlag GmbH 
690 7 |a Crystallography  |2 nationallicence 
690 7 |a Inorganic chemistry  |2 nationallicence 
690 7 |a Organic chemistry  |2 nationallicence 
700 1 |a Baker  |D Shenda M.  |4 aut 
700 1 |a Kolthammer  |D W. Stephen  |4 aut 
700 1 |a Tan  |D Johannes B.  |4 aut 
700 1 |a Smith  |D Gregory S.  |4 aut 
773 0 |t Zeitschrift für Kristallographie - Crystalline Materials  |d De Gruyter Oldenbourg  |g 219/3(2004-03-01), 179-185  |x 2194-4946  |q 219:3<179  |1 2004  |2 219  |o zkri 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Baker  |D Shenda M.  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kolthammer  |D W. Stephen  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Tan  |D Johannes B.  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Smith  |D Gregory S.  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Zeitschrift für Kristallographie - Crystalline Materials  |d De Gruyter Oldenbourg  |g 219/3(2004-03-01), 179-185  |x 2194-4946  |q 219:3<179  |1 2004  |2 219  |o zkri 
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