caa a22 4500 378896032 CHVBK 20180305123506.0 cr unu---uuuuu 161128e20041201xx s 000 0 eng 10.1515/BC.2004.147 doi (NATIONALLICENCE)gruyter-10.1515/BC.2004.147 Neuroendocrine regulation of salivary IgA synthesis and secretion: implications for oral health [Elektronische Daten] [Wijnand Teeuw, Jos A. Bosch, Enno C.I. Veerman, Arie V. Nieuw Amerongen] Secretory immunoglobulin A (S-IgA) represents the main adaptive immune mechanism in the oral cavity. The regulation of secretion and synthesis of S-IgA is not only dependent on prior antigenic stimulation, but is also under strong neuroendocrine control. Thus, alterations in neuroendocrine functioning (such as induced by stress, exercise, pregnancy, menstrual cycle, and pharmacological interventions) may affect salivary IgA levels. This review deals with the neuroendocrine regulation of synthesis and secretion of salivary IgA and its potential role in the maintenance of oral health. ©2004 by Walter de Gruyter Berlin New York Biochemistry nationallicence Molecular biology nationallicence Cellular biology nationallicence exocrine glands nationallicence immunoglobulins nationallicence mucosa nationallicence saliva nationallicence salivary gland nationallicence Teeuw Wijnand Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, NL-1018 BT Amsterdam, The Netherlands aut Bosch Jos A. School of Sport and Exercise Sciences, University of Birmingham, Birmingham B15 2TT, UK aut Veerman Enno C.I. Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, NL-1018 BT Amsterdam, The Netherlands aut Nieuw Amerongen Arie V. Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, NL-1018 BT Amsterdam, The Netherlands aut Biological Chemistry Walter de Gruyter 385/12(2004-12-01), 1137-1146 1431-6730 385:12<1137 2004 385 bchm https://doi.org/10.1515/BC.2004.147 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1515/BC.2004.147 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Teeuw Wijnand Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, NL-1018 BT Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Bosch Jos A. School of Sport and Exercise Sciences, University of Birmingham, Birmingham B15 2TT, UK aut NATIONALLICENCE 700 1- Veerman Enno C.I. Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, NL-1018 BT Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Nieuw Amerongen Arie V. Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, NL-1018 BT Amsterdam, The Netherlands aut NATIONALLICENCE 773 0- Biological Chemistry Walter de Gruyter 385/12(2004-12-01), 1137-1146 1431-6730 385:12<1137 2004 385 bchm CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter