caa a22 4500 37889787X CHVBK 20180305123510.0 cr unu---uuuuu 161128e20040216xx s 000 0 eng 10.1515/CCLM.2004.015 doi (NATIONALLICENCE)gruyter-10.1515/CCLM.2004.015 Analytical goals for coagulation tests based on biological variation [Elektronische Daten] [Yui Wada, Masako Kurihara, Mitsuko Toyofuku, Minako Kawamura, Hiroko Iida, Yuzou Kayamori, Sachiko Kinoshita, Naotaka Hamasaki] Allowable imprecision and bias reference limits for laboratory data can be calculated based on measurements of biological variation. Although biological variation of clinical chemical data has been reported from many laboratories, there have been few reports of biological variation in coagulation tests. In this study, we calculated the biological variation of 13 coagulation tests in the clinical laboratory of Kyushu University Hospital and determined allowable imprecision and bias limits of variation. The participating subjects were 17 healthy individuals: three males and two females in their 20s, two males and two females in their 30s, one male and four females in their 40s, and two males and one female in their 50s. Monthly measurements were performed before breakfast 12 times from June 2001 to May 2002 and allowable imprecision and bias limits were calculated. Taken together with coefficient of variation of control plasma used in daily laboratory work at the hospital, the allowable imprecision limits of intra-laboratory variation determined in this study appear to be in attainable ranges. Copyright (c) 2004 by Walter de Gruyter GmbH & Co. KG Medical equipment & techniques nationallicence Medical diagnosis nationallicence Diseases & disorders nationallicence Wada Yui aut Kurihara Masako aut Toyofuku Mitsuko aut Kawamura Minako aut Iida Hiroko aut Kayamori Yuzou aut Kinoshita Sachiko aut Hamasaki Naotaka aut Clinical Chemistry and Laboratory Medicine Walter de Gruyter 42/1(2004-02-16), 79-83 1434-6621 42:1<79 2004 42 cclm https://doi.org/10.1515/CCLM.2004.015 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1515/CCLM.2004.015 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wada Yui aut NATIONALLICENCE 700 1- Kurihara Masako aut NATIONALLICENCE 700 1- Toyofuku Mitsuko aut NATIONALLICENCE 700 1- Kawamura Minako aut NATIONALLICENCE 700 1- Iida Hiroko aut NATIONALLICENCE 700 1- Kayamori Yuzou aut NATIONALLICENCE 700 1- Kinoshita Sachiko aut NATIONALLICENCE 700 1- Hamasaki Naotaka aut NATIONALLICENCE 773 0- Clinical Chemistry and Laboratory Medicine Walter de Gruyter 42/1(2004-02-16), 79-83 1434-6621 42:1<79 2004 42 cclm CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter