caa a22 4500 37890731X CHVBK 20180305123533.0 cr unu---uuuuu 161128e20040401xx s 000 0 eng 10.1524/ract.92.4.285.35587 doi (NATIONALLICENCE)gruyter-10.1524/ract.92.4.285.35587 Analysis of 188Re-EDTMP complexes by HPLC and ultrafiltration [Elektronische Daten] [Kazuyuki Hashimoto, Hiromitsu Matsuoka] High performance liquid chromatography (anion-exchange, reversed-phase ion-pair and gel permeation chromatography) and ultrafiltration have been employed to analyze 188Re-ethylenediamine-N,N,N´,N´-tetrakis(methylenephosphonic acid) complexes ( 188Re-EDTMP), prepared from the tin chloride reduction or sodium borohydride reduction in the presence or absence of rhenium carrier. The HPLC analysis showed that the 188Re-EDTMP complexes were mixtures of components and the distribution of the components was dependent upon the total amount of rhenium present and the reducing agents (SnCl2, NaBH4). The ultrafiltration analysis showed that the distribution of nominal molecular weight of 188Re-EDTMP was dependent upon the presence of rhenium carrier and the reducing agents. In addition, it was found that the proportion of chemical species with bigger molecular weight in no-carrier-added 188Re(SnCl2)-EDTMP was larger than that in carrier-added 188Re(SnCl2)-EDTMP. © 2004 Oldenbourg Wissenschaftsverlag GmbH Laboratory techniques, experiments nationallicence Analytical chemistry nationallicence Inorganic chemistry nationallicence Hashimoto Kazuyuki aut Matsuoka Hiromitsu aut Radiochimica Acta/International journal for chemical aspects of nuclear science and technology Oldenbourg Wissenschaftsverlag GmbH 92/4-6/2004(2004-04-01), 285-290 0033-8230 92:4-6/2004<285 2004 92 ract https://doi.org/10.1524/ract.92.4.285.35587 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1524/ract.92.4.285.35587 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hashimoto Kazuyuki aut NATIONALLICENCE 700 1- Matsuoka Hiromitsu aut NATIONALLICENCE 773 0- Radiochimica Acta/International journal for chemical aspects of nuclear science and technology Oldenbourg Wissenschaftsverlag GmbH 92/4-6/2004(2004-04-01), 285-290 0033-8230 92:4-6/2004<285 2004 92 ract CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter