caa a22 4500 378911317 CHVBK 20180305123542.0 cr unu---uuuuu 161128e20040101xx s 000 0 eng 10.1351/pac200476050941 doi (NATIONALLICENCE)gruyter-10.1351/pac200476050941 Neuropeptide mimetics for pain management [Elektronische Daten] [A. W. Lipkowski, A. Misicka, D. B. Carr, G. Ronsisvalle, Dariusz Kosson, I. Maszczynska Bonney] The discovery of numerous endogenous neuropeptides that participate in the formation, transmission, modulation, and perception of pain signals offers numerous strategies for the development of new analgesics. Nevertheless, the same research has not yet replaced opioids as the gold standard of pain treatment. Therefore, one possible avenue of drug development may shift interest from searching for receptor-selective opioids to creating an arsenal of drugs that target multiple opioid and non-opioid sites simultaneously. The presented short review focuses on the development of potential analgesic peptidomimetic compounds based upon opioid neuropeptides and substance P. © 2013 Walter de Gruyter GmbH, Berlin/Boston Lipkowski A. W. Medical Research Centre, Polish Academy of Sciences, 02106 Warsaw, Poland; Department of Chemistry, Warsaw University, 02-093 Warsaw, Poland; Tufts-New England Medical Center, Boston, MA 02111, USA; Department of Pharmaceutical Sciences, University of Catania, 95125 Catania, Italy; Department of Anesthesia and Intensive Care, Medical School, Warsaw, Poland aut Misicka A. Medical Research Centre, Polish Academy of Sciences, 02106 Warsaw, Poland; Department of Chemistry, Warsaw University, 02-093 Warsaw, Poland; Tufts-New England Medical Center, Boston, MA 02111, USA; Department of Pharmaceutical Sciences, University of Catania, 95125 Catania, Italy; Department of Anesthesia and Intensive Care, Medical School, Warsaw, Poland aut Carr D. B. Medical Research Centre, Polish Academy of Sciences, 02106 Warsaw, Poland; Department of Chemistry, Warsaw University, 02-093 Warsaw, Poland; Tufts-New England Medical Center, Boston, MA 02111, USA; Department of Pharmaceutical Sciences, University of Catania, 95125 Catania, Italy; Department of Anesthesia and Intensive Care, Medical School, Warsaw, Poland aut Ronsisvalle G. Medical Research Centre, Polish Academy of Sciences, 02106 Warsaw, Poland; Department of Chemistry, Warsaw University, 02-093 Warsaw, Poland; Tufts-New England Medical Center, Boston, MA 02111, USA; Department of Pharmaceutical Sciences, University of Catania, 95125 Catania, Italy; Department of Anesthesia and Intensive Care, Medical School, Warsaw, Poland aut Kosson Dariusz Medical Research Centre, Polish Academy of Sciences, 02106 Warsaw, Poland; Department of Chemistry, Warsaw University, 02-093 Warsaw, Poland; Tufts-New England Medical Center, Boston, MA 02111, USA; Department of Pharmaceutical Sciences, University of Catania, 95125 Catania, Italy; Department of Anesthesia and Intensive Care, Medical School, Warsaw, Poland aut Bonney I. Maszczynska Medical Research Centre, Polish Academy of Sciences, 02106 Warsaw, Poland; Department of Chemistry, Warsaw University, 02-093 Warsaw, Poland; Tufts-New England Medical Center, Boston, MA 02111, USA; Department of Pharmaceutical Sciences, University of Catania, 95125 Catania, Italy; Department of Anesthesia and Intensive Care, Medical School, Warsaw, Poland aut Pure and Applied Chemistry De Gruyter 76/5(2004-01-01), 941-950 0033-4545 76:5<941 2004 76 pac https://doi.org/10.1351/pac200476050941 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1351/pac200476050941 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lipkowski A. W. Medical Research Centre, Polish Academy of Sciences, 02106 Warsaw, Poland; Department of Chemistry, Warsaw University, 02-093 Warsaw, Poland; Tufts-New England Medical Center, Boston, MA 02111, USA; Department of Pharmaceutical Sciences, University of Catania, 95125 Catania, Italy; Department of Anesthesia and Intensive Care, Medical School, Warsaw, Poland aut NATIONALLICENCE 700 1- Misicka A. Medical Research Centre, Polish Academy of Sciences, 02106 Warsaw, Poland; Department of Chemistry, Warsaw University, 02-093 Warsaw, Poland; Tufts-New England Medical Center, Boston, MA 02111, USA; Department of Pharmaceutical Sciences, University of Catania, 95125 Catania, Italy; Department of Anesthesia and Intensive Care, Medical School, Warsaw, Poland aut NATIONALLICENCE 700 1- Carr D. B. Medical Research Centre, Polish Academy of Sciences, 02106 Warsaw, Poland; Department of Chemistry, Warsaw University, 02-093 Warsaw, Poland; Tufts-New England Medical Center, Boston, MA 02111, USA; Department of Pharmaceutical Sciences, University of Catania, 95125 Catania, Italy; Department of Anesthesia and Intensive Care, Medical School, Warsaw, Poland aut NATIONALLICENCE 700 1- Ronsisvalle G. Medical Research Centre, Polish Academy of Sciences, 02106 Warsaw, Poland; Department of Chemistry, Warsaw University, 02-093 Warsaw, Poland; Tufts-New England Medical Center, Boston, MA 02111, USA; Department of Pharmaceutical Sciences, University of Catania, 95125 Catania, Italy; Department of Anesthesia and Intensive Care, Medical School, Warsaw, Poland aut NATIONALLICENCE 700 1- Kosson Dariusz Medical Research Centre, Polish Academy of Sciences, 02106 Warsaw, Poland; Department of Chemistry, Warsaw University, 02-093 Warsaw, Poland; Tufts-New England Medical Center, Boston, MA 02111, USA; Department of Pharmaceutical Sciences, University of Catania, 95125 Catania, Italy; Department of Anesthesia and Intensive Care, Medical School, Warsaw, Poland aut NATIONALLICENCE 700 1- Bonney I. Maszczynska Medical Research Centre, Polish Academy of Sciences, 02106 Warsaw, Poland; Department of Chemistry, Warsaw University, 02-093 Warsaw, Poland; Tufts-New England Medical Center, Boston, MA 02111, USA; Department of Pharmaceutical Sciences, University of Catania, 95125 Catania, Italy; Department of Anesthesia and Intensive Care, Medical School, Warsaw, Poland aut NATIONALLICENCE 773 0- Pure and Applied Chemistry De Gruyter 76/5(2004-01-01), 941-950 0033-4545 76:5<941 2004 76 pac CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter