caa a22 4500 37891362X CHVBK 20180305123547.0 cr unu---uuuuu 161128e20040401xx s 000 0 eng 10.1524/zpch.218.4.425.29197 doi (NATIONALLICENCE)gruyter-10.1524/zpch.218.4.425.29197 Aggregation of 1-Palmitoyl-2-Oleoyl-Sn-Glycero-3-Phosphocholine in Nonaqueous Solutions Studied by Spectroscopic and Kinetic Probe Molecules and Dynamic Light Scattering [Elektronische Daten] [Shaoying Wen, Bernd Kohlstrunk, Martin Helmstedt, Helmut Knoll] The aggregation behavior of 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) in the nonaqueous solvents formamide (FA) and 3-hydroxypropionitrile (HPN) has been studied. UV/Vis absorption maximum λmax and thermal cis → trans isomerization rate constant kiso of an azo dye, as well as fluorescence intensity ratios IM/IE of monomer and excimer, and the excimer lifetime τE of two dipyrenyl compounds as probe molecules have been determined. For comparison, aggregation of the amphiphile POPC molecules was followed "probe-free” by means of dynamic light scattering (DLS) measurements. Combining the results of probe molecule studies and DLS it turned out that the critical aggregation concentration of POPC in FA < 0.05mmol dm−3. At ≥ 0.2mmol dm−3, aggregates have hydrodynamic radii 30 < Rh < 80nm and high microviscosity in their hydrocarbon interior. A vesicle-like structure of the aggregates can therefore be assumed. Aggregation behavior of POPC in HPN is much less pronounced, essentially small aggregates with radii of a few nanometer have been detected which include solvent molecules. © 2004 Oldenbourg Wissenschaftsverlag GmbH Thermodynamics & statistical physics nationallicence Laboratory techniques, experiments nationallicence Physical chemistry nationallicence Wen Shaoying aut Kohlstrunk Bernd aut Helmstedt Martin aut Knoll Helmut aut Zeitschrift für Physikalische Chemie/International journal of research in physical chemistry and chemical physics Oldenbourg Wissenschaftsverlag GmbH 218/4/2004(2004-04-01), 425-438 0942-9352 218:4/2004<425 2004 218 zpch https://doi.org/10.1524/zpch.218.4.425.29197 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1524/zpch.218.4.425.29197 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wen Shaoying aut NATIONALLICENCE 700 1- Kohlstrunk Bernd aut NATIONALLICENCE 700 1- Helmstedt Martin aut NATIONALLICENCE 700 1- Knoll Helmut aut NATIONALLICENCE 773 0- Zeitschrift für Physikalische Chemie/International journal of research in physical chemistry and chemical physics Oldenbourg Wissenschaftsverlag GmbH 218/4/2004(2004-04-01), 425-438 0942-9352 218:4/2004<425 2004 218 zpch CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter