The chemistry of nitrosative stress induced by nitric oxide and reactive nitrogen oxide species. Putting perspective on stressful biological situations
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| 008 | 161128e20040105xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.1515/BC.2004.001 |2 doi |
| 035 | |a (NATIONALLICENCE)gruyter-10.1515/BC.2004.001 | ||
| 245 | 0 | 4 | |a The chemistry of nitrosative stress induced by nitric oxide and reactive nitrogen oxide species. Putting perspective on stressful biological situations |h [Elektronische Daten] |c [L. A. Ridnour, D. D. Thomas, D. Mancardi, M. G. Espey, K. M. Miranda, N. Paolocci, M. Feelisch, J. Fukuto, D. A. Wink] |
| 520 | 3 | |a This review addresses many of the chemical aspects of nitrosative stress mediated by N(2)O(3). From a cellular perspective, N(2)O(3) and the resulting reactive nitrogen oxide species target specific motifs such as thiols, lysine active sites, and zinc fingers and is dependant upon both the rates of production as well as consumption of NO and must be taken into account in order to access the nitrosative environment. Since production and consumption are integral parts of N(2)O(3) generation, we predict that nitrosative stress occurs under specific conditions, such as chronic inflammation. In contrast to conditions of stress, nitrosative chemistry may also provide cellular protection through the regulation of critical signaling pathways. Therefore, a careful evaluation of the chemistry of nitrosation based upon specific experimental conditions may provide a better understanding of how the subtle balance between oxidative and nitrosative stress may be involved in the etiology and control of various disease processes. | |
| 540 | |a Copyright © 2004 by Walter de Gruyter GmbH & Co. KG | ||
| 690 | 7 | |a Biochemistry |2 nationallicence | |
| 690 | 7 | |a Molecular biology |2 nationallicence | |
| 690 | 7 | |a Cellular biology |2 nationallicence | |
| 700 | 1 | |a Ridnour |D L. A. |4 aut | |
| 700 | 1 | |a Thomas |D D. D. |4 aut | |
| 700 | 1 | |a Mancardi |D D. |4 aut | |
| 700 | 1 | |a Espey |D M. G. |4 aut | |
| 700 | 1 | |a Miranda |D K. M. |4 aut | |
| 700 | 1 | |a Paolocci |D N. |4 aut | |
| 700 | 1 | |a Feelisch |D M. |4 aut | |
| 700 | 1 | |a Fukuto |D J. |4 aut | |
| 700 | 1 | |a Wink |D D. A. |4 aut | |
| 773 | 0 | |t Biological Chemistry |d Walter de Gruyter |g 385/1(2004-01-05), 1-10 |x 1431-6730 |q 385:1<1 |1 2004 |2 385 |o bchm | |
| 856 | 4 | 0 | |u https://doi.org/10.1515/BC.2004.001 |q text/html |z Onlinezugriff via DOI |
| 908 | |D 1 |a research article |2 jats | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1515/BC.2004.001 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ridnour |D L. A. |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Thomas |D D. D. |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Mancardi |D D. |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Espey |D M. G. |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Miranda |D K. M. |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Paolocci |D N. |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Feelisch |D M. |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Fukuto |D J. |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Wink |D D. A. |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Biological Chemistry |d Walter de Gruyter |g 385/1(2004-01-05), 1-10 |x 1431-6730 |q 385:1<1 |1 2004 |2 385 |o bchm | ||
| 900 | 7 | |b CC0 |u http://creativecommons.org/publicdomain/zero/1.0 |2 nationallicence | |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-gruyter | ||