Massive hepatic infarction in preeclampsia: successful treatment with continuous hemodiafiltration and corticosteroid therapy

Verfasser / Beitragende:
[Kei Miyakoshi, Mamoru Tanaka, Akiko Ono, Akiko Ohno, Ryohei Serita, Takeshi Suzuki, Hiroshi Shinmoto, Hiroshi Morisaki, Yasunori Yoshimura]
Ort, Verlag, Jahr:
2004
Enthalten in:
Journal of Perinatal Medicine, 32/5(2004-09-01), 453-455
Format:
Artikel (online)
ID: 37891720X
LEADER caa a22 4500
001 37891720X
003 CHVBK
005 20180305123556.0
007 cr unu---uuuuu
008 161128e20040901xx s 000 0 eng
024 7 0 |a 10.1515/JPM.2004.146  |2 doi 
035 |a (NATIONALLICENCE)gruyter-10.1515/JPM.2004.146 
245 0 0 |a Massive hepatic infarction in preeclampsia: successful treatment with continuous hemodiafiltration and corticosteroid therapy  |h [Elektronische Daten]  |c [Kei Miyakoshi, Mamoru Tanaka, Akiko Ono, Akiko Ohno, Ryohei Serita, Takeshi Suzuki, Hiroshi Shinmoto, Hiroshi Morisaki, Yasunori Yoshimura] 
520 3 |a Massive hepatic infarction associated with pregnancy is extremely rare, but is potentially fatal. A 35-year-old primigravida with mild preeclampsia developed acute right upper quadrant pain and marked elevation of liver enzymes at 26 weeks' gestation. After emergent cesarean section, her condition was complicated by oliguric renal failure and pulmonary edema with further deterioration of hepatic function (aspartate transaminase 4339 IU/L; alanine transaminase 3489 IU/L; lactate dehydrogenase 10780 IU/L). The contrast-enhanced computed tomography revealed non-enhancing low attenuation throughout the right lobe of liver, compatible with infarction. Continuous hemodiafiltration was initiated as renal support on postpartum day one. However, excessive fluid accumulation persisted, and she developed severe edema formation in both lung and systemic body surface. To ameliorate microvascular endothelial injury, corticosteroid therapy was begun on postpartum day five. Following treatment initiation, her renal and hepatic function showed steady improvement, accompanied by drastic resolution of edema formation. She was discharged five weeks postpartum with no additional treatment, and is without sequelae six months later. Massive hepatic infarction should be considered in preeclamptic patients who present acute abdominal pain and severe hepatic dysfunction, and continuous hemodiafiltration with corticosteroid therapy may improve the maternal outcome. 
540 |a © Walter de Gruyter 
690 7 |a Human reproduction, growth & development  |2 nationallicence 
690 7 |a Gynaecology & obstetrics  |2 nationallicence 
690 7 |a Paediatric medicine  |2 nationallicence 
690 7 |a Continuous hemodiafiltration  |2 nationallicence 
690 7 |a corticosteroid  |2 nationallicence 
690 7 |a hepatic infarction  |2 nationallicence 
690 7 |a preeclampsia  |2 nationallicence 
700 1 |a Miyakoshi  |D Kei  |u Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan  |4 aut 
700 1 |a Tanaka  |D Mamoru  |u Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan  |4 aut 
700 1 |a Ono  |D Akiko  |u Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan  |4 aut 
700 1 |a Ohno  |D Akiko  |u Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan  |4 aut 
700 1 |a Serita  |D Ryohei  |u Department of Anesthesiology, Keio University School of Medicine, Tokyo, Japan  |4 aut 
700 1 |a Suzuki  |D Takeshi  |u Department of Anesthesiology, Keio University School of Medicine, Tokyo, Japan  |4 aut 
700 1 |a Shinmoto  |D Hiroshi  |u Department of Diagnostic Radiology, Keio University School of Medicine, Tokyo, Japan  |4 aut 
700 1 |a Morisaki  |D Hiroshi  |u Department of Anesthesiology, Keio University School of Medicine, Tokyo, Japan  |4 aut 
700 1 |a Yoshimura  |D Yasunori  |u Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan  |4 aut 
773 0 |t Journal of Perinatal Medicine  |d Walter de Gruyter  |g 32/5(2004-09-01), 453-455  |x 0300-5577  |q 32:5<453  |1 2004  |2 32  |o jpme 
856 4 0 |u https://doi.org/10.1515/JPM.2004.146  |q text/html  |z Onlinezugriff via DOI 
908 |D 1  |a research article  |2 jats 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1515/JPM.2004.146  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Miyakoshi  |D Kei  |u Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Tanaka  |D Mamoru  |u Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ono  |D Akiko  |u Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ohno  |D Akiko  |u Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Serita  |D Ryohei  |u Department of Anesthesiology, Keio University School of Medicine, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Suzuki  |D Takeshi  |u Department of Anesthesiology, Keio University School of Medicine, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Shinmoto  |D Hiroshi  |u Department of Diagnostic Radiology, Keio University School of Medicine, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Morisaki  |D Hiroshi  |u Department of Anesthesiology, Keio University School of Medicine, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yoshimura  |D Yasunori  |u Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Journal of Perinatal Medicine  |d Walter de Gruyter  |g 32/5(2004-09-01), 453-455  |x 0300-5577  |q 32:5<453  |1 2004  |2 32  |o jpme 
900 7 |b CC0  |u http://creativecommons.org/publicdomain/zero/1.0  |2 nationallicence 
898 |a BK010053  |b XK010053  |c XK010000 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-gruyter