The use of recombinant factor VIIa in a primigravida with Glanzmann's thrombasthenia during delivery

Verfasser / Beitragende:
[Ahmet Kale, Gokhan Bayhan, Ahmet Yalinkaya, Murat Yayla]
Ort, Verlag, Jahr:
2004
Enthalten in:
Journal of Perinatal Medicine, 32/5(2004-09-01), 456-458
Format:
Artikel (online)
ID: 378917242
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024 7 0 |a 10.1515/JPM.2004.147  |2 doi 
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245 0 4 |a The use of recombinant factor VIIa in a primigravida with Glanzmann's thrombasthenia during delivery  |h [Elektronische Daten]  |c [Ahmet Kale, Gokhan Bayhan, Ahmet Yalinkaya, Murat Yayla] 
520 3 |a Glanzmann's thrombasthenia is an inherited hemorrhagic disorder characterized by a severe reduction in, or absence of, platelet aggregation in response to multiple physiologic agonists due to qualitative or quantitative abnormalities of platelet glycoprotein IIb-IIIa. Glanzmann's thrombasthenia is characterized by potentially major mucocutaneous bleeding and prolonged bleeding time. Platelet counts, platelet morphology, prothrombin, and activated thromboplastin times are all within normal ranges in patients with Glanzmann's thrombasthenia. Pregnancy and delivery are rare in Glanzmann thrombasthenia patients and have been associated with immediate postpartum hemorrhage. We describe the peripartum management of a 31-year-old primipara with Glanzmann's thrombasthenia who underwent spontaneous vaginal delivery. Four units of single-donor platelets, two units of packed red blood cells, 36 µg/kg recombinant human coagulation Factor VIIa (rFVIIa) were given during peripartum management. 
540 |a © Walter de Gruyter 
690 7 |a Human reproduction, growth & development  |2 nationallicence 
690 7 |a Gynaecology & obstetrics  |2 nationallicence 
690 7 |a Paediatric medicine  |2 nationallicence 
690 7 |a Glanzmann's thrombasthenia  |2 nationallicence 
690 7 |a platelet transfusion  |2 nationallicence 
690 7 |a postpartum hemorrhage  |2 nationallicence 
690 7 |a pregnancy  |2 nationallicence 
690 7 |a recombinant human coagulation factor VIIa (rFVIIa)  |2 nationallicence 
700 1 |a Kale  |D Ahmet  |u Department of Obstetrics and Gynecology, Dicle University School of Medicine, Diyarbakir, Turkey  |4 aut 
700 1 |a Bayhan  |D Gokhan  |u Department of Obstetrics and Gynecology, Dicle University School of Medicine, Diyarbakir, Turkey  |4 aut 
700 1 |a Yalinkaya  |D Ahmet  |u Department of Obstetrics and Gynecology, Dicle University School of Medicine, Diyarbakir, Turkey  |4 aut 
700 1 |a Yayla  |D Murat  |u Department of Obstetrics and Gynecology, Dicle University School of Medicine, Diyarbakir, Turkey  |4 aut 
773 0 |t Journal of Perinatal Medicine  |d Walter de Gruyter  |g 32/5(2004-09-01), 456-458  |x 0300-5577  |q 32:5<456  |1 2004  |2 32  |o jpme 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kale  |D Ahmet  |u Department of Obstetrics and Gynecology, Dicle University School of Medicine, Diyarbakir, Turkey  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Bayhan  |D Gokhan  |u Department of Obstetrics and Gynecology, Dicle University School of Medicine, Diyarbakir, Turkey  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yalinkaya  |D Ahmet  |u Department of Obstetrics and Gynecology, Dicle University School of Medicine, Diyarbakir, Turkey  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yayla  |D Murat  |u Department of Obstetrics and Gynecology, Dicle University School of Medicine, Diyarbakir, Turkey  |4 aut 
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