Etiology of cerebral palsy

Verfasser / Beitragende:
[Alf Meberg, Harald Broch]
Ort, Verlag, Jahr:
2004
Enthalten in:
Journal of Perinatal Medicine, 32/5(2004-09-01), 434-439
Format:
Artikel (online)
ID: 378917269
LEADER caa a22 4500
001 378917269
003 CHVBK
005 20180305123556.0
007 cr unu---uuuuu
008 161128e20040901xx s 000 0 eng
024 7 0 |a 10.1515/JPM.2004.143  |2 doi 
035 |a (NATIONALLICENCE)gruyter-10.1515/JPM.2004.143 
245 0 0 |a Etiology of cerebral palsy  |h [Elektronische Daten]  |c [Alf Meberg, Harald Broch] 
520 3 |a Aims: To register the prevalence of cerebral palsy (CP) and determine etiological factors for the condition. Methods: Population based study with registration of CP-cases in children born during the 30-year period 1970-99. Cases with postneonatal etiology were excluded. Results: 166 CP-cases were registered among 70 824 children, a prevalence of 2.3 per 1000 live born infants. The prevalence did not change significantly during the period. 66 (40%) were low birthweight infants (LBWIs; <2500 g), and 100 (60%) normal birthweight infants (NBWIs; ≥2500 g). The origin was classified as prenatal in 37 (22%), perinatal/neonatal in 78 (47%) and unclassifiable in 51 (31%). In LBWIs 39/66 (59%) had a perinatal/neonatal etiology, most frequently intra- or periventricular hemorrhages (IVH/PVH) and/or periventricular leukomalacia (PVL) or cerebral infarctions (CI) (17; 44%). In NBWIs 39/100 (39%) had a perinatal etiology, most frequently hypoxic-ischemic encephalopathy (HIE) (31; 79%). Conclusions: In a substantial percentage of CP-cases perinatal/neonatal brain injury was classified as the cause. Among these IVH/PVH/PVL/CI dominated in LBWIs, while HIE dominated in NBWIs. Our data may point to preventability of a larger part of CP than earlier suggested. 
540 |a © Walter de Gruyter 
690 7 |a Human reproduction, growth & development  |2 nationallicence 
690 7 |a Gynaecology & obstetrics  |2 nationallicence 
690 7 |a Paediatric medicine  |2 nationallicence 
690 7 |a Cerebral infarction  |2 nationallicence 
690 7 |a cerebral palsy  |2 nationallicence 
690 7 |a etiological factors  |2 nationallicence 
690 7 |a neonatal encephalopathy  |2 nationallicence 
690 7 |a neonatal mortality  |2 nationallicence 
690 7 |a periventricular hemorrhage  |2 nationallicence 
690 7 |a periventricular leukomalacia  |2 nationallicence 
700 1 |a Meberg  |D Alf  |u Department of Paediatrics, Vestfold Hospital Tønsberg, Norway  |4 aut 
700 1 |a Broch  |D Harald  |u Department of Paediatrics, Vestfold Hospital Tønsberg, Norway  |4 aut 
773 0 |t Journal of Perinatal Medicine  |d Walter de Gruyter  |g 32/5(2004-09-01), 434-439  |x 0300-5577  |q 32:5<434  |1 2004  |2 32  |o jpme 
856 4 0 |u https://doi.org/10.1515/JPM.2004.143  |q text/html  |z Onlinezugriff via DOI 
908 |D 1  |a research article  |2 jats 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1515/JPM.2004.143  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Meberg  |D Alf  |u Department of Paediatrics, Vestfold Hospital Tønsberg, Norway  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Broch  |D Harald  |u Department of Paediatrics, Vestfold Hospital Tønsberg, Norway  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Journal of Perinatal Medicine  |d Walter de Gruyter  |g 32/5(2004-09-01), 434-439  |x 0300-5577  |q 32:5<434  |1 2004  |2 32  |o jpme 
900 7 |b CC0  |u http://creativecommons.org/publicdomain/zero/1.0  |2 nationallicence 
898 |a BK010053  |b XK010053  |c XK010000 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-gruyter