caa a22 4500 378917269 CHVBK 20180305123556.0 cr unu---uuuuu 161128e20040901xx s 000 0 eng 10.1515/JPM.2004.143 doi (NATIONALLICENCE)gruyter-10.1515/JPM.2004.143 Etiology of cerebral palsy [Elektronische Daten] [Alf Meberg, Harald Broch] Aims: To register the prevalence of cerebral palsy (CP) and determine etiological factors for the condition. Methods: Population based study with registration of CP-cases in children born during the 30-year period 1970-99. Cases with postneonatal etiology were excluded. Results: 166 CP-cases were registered among 70 824 children, a prevalence of 2.3 per 1000 live born infants. The prevalence did not change significantly during the period. 66 (40%) were low birthweight infants (LBWIs; <2500 g), and 100 (60%) normal birthweight infants (NBWIs; ≥2500 g). The origin was classified as prenatal in 37 (22%), perinatal/neonatal in 78 (47%) and unclassifiable in 51 (31%). In LBWIs 39/66 (59%) had a perinatal/neonatal etiology, most frequently intra- or periventricular hemorrhages (IVH/PVH) and/or periventricular leukomalacia (PVL) or cerebral infarctions (CI) (17; 44%). In NBWIs 39/100 (39%) had a perinatal etiology, most frequently hypoxic-ischemic encephalopathy (HIE) (31; 79%). Conclusions: In a substantial percentage of CP-cases perinatal/neonatal brain injury was classified as the cause. Among these IVH/PVH/PVL/CI dominated in LBWIs, while HIE dominated in NBWIs. Our data may point to preventability of a larger part of CP than earlier suggested. © Walter de Gruyter Human reproduction, growth & development nationallicence Gynaecology & obstetrics nationallicence Paediatric medicine nationallicence Cerebral infarction nationallicence cerebral palsy nationallicence etiological factors nationallicence neonatal encephalopathy nationallicence neonatal mortality nationallicence periventricular hemorrhage nationallicence periventricular leukomalacia nationallicence Meberg Alf Department of Paediatrics, Vestfold Hospital Tønsberg, Norway aut Broch Harald Department of Paediatrics, Vestfold Hospital Tønsberg, Norway aut Journal of Perinatal Medicine Walter de Gruyter 32/5(2004-09-01), 434-439 0300-5577 32:5<434 2004 32 jpme https://doi.org/10.1515/JPM.2004.143 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1515/JPM.2004.143 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Meberg Alf Department of Paediatrics, Vestfold Hospital Tønsberg, Norway aut NATIONALLICENCE 700 1- Broch Harald Department of Paediatrics, Vestfold Hospital Tønsberg, Norway aut NATIONALLICENCE 773 0- Journal of Perinatal Medicine Walter de Gruyter 32/5(2004-09-01), 434-439 0300-5577 32:5<434 2004 32 jpme CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter