caa a22 4500 378917277 CHVBK 20180305123556.0 cr unu---uuuuu 161128e20040901xx s 000 0 eng 10.1515/JPM.2004.140 doi (NATIONALLICENCE)gruyter-10.1515/JPM.2004.140 Comparison of intrapartum fetal heart rate tracings in patients with neonatal seizures vs. no seizures: what are the differences? [Elektronische Daten] [Keith P. Williams, France Galerneau] Objective: To determine which intrapartum fetal heart rate parameters in the presence of severe neonatal acidosis (pH < 7.0) appropriately predicts the development of neonatal seizures in the context of hypoxic ischemic encephalopathy (HIE). Methods: The intrapartum fetal heart rate tracings of 25 neonates who developed neonatal seizures secondary to HIE were compared with 25 matched neonates with similar pH and gestational age who did not develop seizures. All patients had at least 2 hours of intrapartum fetal heart rate patterns available for review. We compared the fetal heart rate parameters of prolonged deceleration, variable and late decelerations, variability, accelerations, fetal heart rate baseline and duration of the fetal heart rate abnormality. Comparison between the groups was done using chi-square for nominal data and student t-tests for continuous data. Results: Neonates with seizures 2° HIE had a significantly longer duration of abnormal fetal heart rate patterns (72 ± 12 minutes vs 48 ± 12 minutes, p < 0.001). Discussion: This study demonstrated that in the setting of neonatal acidosis the development of seizures is related to the period of stress (duration of the abnormal fetal heart rate pattern). © Walter de Gruyter Human reproduction, growth & development nationallicence Gynaecology & obstetrics nationallicence Paediatric medicine nationallicence Intrapartum fetal heart rate nationallicence cesarean section nationallicence neonatal acidemia nationallicence Williams Keith P. Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, U.S.A. aut Galerneau France Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, U.S.A. aut Journal of Perinatal Medicine Walter de Gruyter 32/5(2004-09-01), 422-425 0300-5577 32:5<422 2004 32 jpme https://doi.org/10.1515/JPM.2004.140 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1515/JPM.2004.140 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Williams Keith P. Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, U.S.A aut NATIONALLICENCE 700 1- Galerneau France Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, U.S.A aut NATIONALLICENCE 773 0- Journal of Perinatal Medicine Walter de Gruyter 32/5(2004-09-01), 422-425 0300-5577 32:5<422 2004 32 jpme CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter