Maternal and fetal insulin-like growth factors 1 and 2 (IGF-1, IGF-2) and IGF BP-3, and their relationship to fetal acidosis at delivery
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| 024 | 7 | 0 | |a 10.1515/JPM.2004.139 |2 doi |
| 035 | |a (NATIONALLICENCE)gruyter-10.1515/JPM.2004.139 | ||
| 245 | 0 | 0 | |a Maternal and fetal insulin-like growth factors 1 and 2 (IGF-1, IGF-2) and IGF BP-3, and their relationship to fetal acidosis at delivery |h [Elektronische Daten] |c [Sharon M. Cooley, Jennifer C. Donnelly, Michael P. Geary, Charles H. Rodeck, Peter C. Hindmarsh] |
| 520 | 3 | |a Objective: To investigate the relationship between levels of insulin-like growth factors 1 and 2 (IGF-1, IGF-2), and insulin-like growth factor binding protein 3 (IGFBP-3) in antenatal maternal serum and in fetal cord blood at delivery. Methods: Prospective cohort study of 1650 low-risk Caucasian women in a University teaching hospital in London. Statistical analysis was performed using commercial software (SPSS for Windows, version 6.1, SPSS, Chicago, Illinois, USA), with p < 0.05 as significant. Maternal IGF 1, IGF 2 and IGF BP-3 were assessed on maternal blood at booking and in fetal blood by cord blood analysis at delivery. Cord pH was also recorded. Results: There was no significant correlation between maternal IGF-1, IGF-2, or IGFBP-3 levels and fetal acidosis. However, a significant correlation does exist between cord IGF-1 levels and fetal acidosis. Conclusion: Fetal cord IGF-1 has a significant correlation with fetal acidosis at delivery. | |
| 540 | |a © Walter de Gruyter | ||
| 690 | 7 | |a Human reproduction, growth & development |2 nationallicence | |
| 690 | 7 | |a Gynaecology & obstetrics |2 nationallicence | |
| 690 | 7 | |a Paediatric medicine |2 nationallicence | |
| 690 | 7 | |a Fetal acidosis |2 nationallicence | |
| 690 | 7 | |a fetal distress |2 nationallicence | |
| 690 | 7 | |a insulin-like growth factor |2 nationallicence | |
| 690 | 7 | |a insulin-like growth factor binding protein |2 nationallicence | |
| 700 | 1 | |a Cooley |D Sharon M. |u Obstetric Research Department, Rotunda Hospital, Dublin, Ireland |4 aut | |
| 700 | 1 | |a Donnelly |D Jennifer C. |4 aut | |
| 700 | 1 | |a Geary |D Michael P. |4 aut | |
| 700 | 1 | |a Rodeck |D Charles H. |4 aut | |
| 700 | 1 | |a Hindmarsh |D Peter C. |4 aut | |
| 773 | 0 | |t Journal of Perinatal Medicine |d Walter de Gruyter |g 32/5(2004-09-01), 418-421 |x 0300-5577 |q 32:5<418 |1 2004 |2 32 |o jpme | |
| 856 | 4 | 0 | |u https://doi.org/10.1515/JPM.2004.139 |q text/html |z Onlinezugriff via DOI |
| 908 | |D 1 |a research article |2 jats | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1515/JPM.2004.139 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Cooley |D Sharon M. |u Obstetric Research Department, Rotunda Hospital, Dublin, Ireland |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Donnelly |D Jennifer C. |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Geary |D Michael P. |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Rodeck |D Charles H. |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Hindmarsh |D Peter C. |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Journal of Perinatal Medicine |d Walter de Gruyter |g 32/5(2004-09-01), 418-421 |x 0300-5577 |q 32:5<418 |1 2004 |2 32 |o jpme | ||
| 900 | 7 | |b CC0 |u http://creativecommons.org/publicdomain/zero/1.0 |2 nationallicence | |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-gruyter | ||