Hair analysis in toxicology

Verfasser / Beitragende:
[Marion Villain, Vincent Cirimele, Pascal Kintz]
Ort, Verlag, Jahr:
2004
Enthalten in:
Clinical Chemistry and Laboratory Medicine, 42/11(2004-11-01), 1265-1272
Format:
Artikel (online)
ID: 378917501
LEADER caa a22 4500
001 378917501
003 CHVBK
005 20180305123557.0
007 cr unu---uuuuu
008 161128e20041101xx s 000 0 eng
024 7 0 |a 10.1515/CCLM.2004.247  |2 doi 
035 |a (NATIONALLICENCE)gruyter-10.1515/CCLM.2004.247 
245 0 0 |a Hair analysis in toxicology  |h [Elektronische Daten]  |c [Marion Villain, Vincent Cirimele, Pascal Kintz] 
520 3 |a Morphological, serological and chemical examination of human hair for medical purposes was initiated some decades ago. In the 1960s and 1970s, hair analysis was used to evaluate exposure to toxic heavy metals. At this time, examination of hair for organic substances, especially drugs, was not possible because analytical methods were not sensitive enough. Since the early 1980s, the development of highly sensitive and specific assay methods such as radioimmunoassay or gas chromatography/mass spectrometry has permitted the analysis of organic substances trapped in hair. This, theoretically, offered the possibility of revealing an individual's recent history of drug exposure beginning at sampling day and dating back over a period of weeks or months. The present review aims to summarise the various applications that have been published. 
540 |a © Walter de Gruyter 
690 7 |a Medical equipment & techniques  |2 nationallicence 
690 7 |a Medical diagnosis  |2 nationallicence 
690 7 |a Diseases & disorders  |2 nationallicence 
690 7 |a abuse  |2 nationallicence 
690 7 |a chromatography  |2 nationallicence 
690 7 |a drugs  |2 nationallicence 
690 7 |a exposure  |2 nationallicence 
690 7 |a hair analysis  |2 nationallicence 
690 7 |a mass spectrometry  |2 nationallicence 
690 7 |a toxicology  |2 nationallicence 
700 1 |a Villain  |D Marion  |u Laboratoire de Toxicologie, Institut de Médecine Légale, Strasbourg, France  |4 aut 
700 1 |a Cirimele  |D Vincent  |u Laboratoire de Toxicologie, Institut de Médecine Légale, Strasbourg and Laboratoire ChemTox, Rue Geiler de Kaysersberg, Illkirch, France  |4 aut 
700 1 |a Kintz  |D Pascal  |u Laboratoire de Toxicologie, Institut de Médecine Légale, Strasbourg, France  |4 aut 
773 0 |t Clinical Chemistry and Laboratory Medicine  |d Walter de Gruyter  |g 42/11(2004-11-01), 1265-1272  |x 1434-6621  |q 42:11<1265  |1 2004  |2 42  |o cclm 
856 4 0 |u https://doi.org/10.1515/CCLM.2004.247  |q text/html  |z Onlinezugriff via DOI 
908 |D 1  |a research article  |2 jats 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1515/CCLM.2004.247  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Villain  |D Marion  |u Laboratoire de Toxicologie, Institut de Médecine Légale, Strasbourg, France  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Cirimele  |D Vincent  |u Laboratoire de Toxicologie, Institut de Médecine Légale, Strasbourg and Laboratoire ChemTox, Rue Geiler de Kaysersberg, Illkirch, France  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kintz  |D Pascal  |u Laboratoire de Toxicologie, Institut de Médecine Légale, Strasbourg, France  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Clinical Chemistry and Laboratory Medicine  |d Walter de Gruyter  |g 42/11(2004-11-01), 1265-1272  |x 1434-6621  |q 42:11<1265  |1 2004  |2 42  |o cclm 
900 7 |b CC0  |u http://creativecommons.org/publicdomain/zero/1.0  |2 nationallicence 
898 |a BK010053  |b XK010053  |c XK010000 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-gruyter