caa a22 4500 378921754 CHVBK 20180305123607.0 cr unu---uuuuu 161128e20040101xx s 000 0 eng 10.1351/pac200476071375 doi (NATIONALLICENCE)gruyter-10.1351/pac200476071375 Dendritic polymers composed of glycerol and succinic acid: Synthetic methodologies and medical applications [Elektronische Daten] [N. R. Luman, Terry Kim, M. W. Grinstaff] Research on dendrimers continues to expand as further advances in synthetic methodology and characterization techniques translate to additional applications. Recently, dendritic polymers composed of the natural metabolites glycerol and succinic acid were synthesized, functionalized, and evaluated as new medical materials. The design and synthesis of poly(glycerol-succinic acid) dendritic polymers are discussed, including comparing and contrasting the convergent versus the divergent methodologies for preparing such macromolecules. Finally, a photocrosslinkable dendritic macromolecule was prepared and successfully used to close linear corneal lacerations as well as to secure LASIK flaps. © 2013 Walter de Gruyter GmbH, Berlin/Boston Luman N. R. Departments of Chemistry and Biomedical Engineering, Metcalf Center for Science and Engineering, Boston University, Boston, MA 02215, USA; Department of Ophthalmology, Duke University Medical Center, Durham, NC 27710, USA aut Kim Terry Departments of Chemistry and Biomedical Engineering, Metcalf Center for Science and Engineering, Boston University, Boston, MA 02215, USA; Department of Ophthalmology, Duke University Medical Center, Durham, NC 27710, USA aut Grinstaff M. W. Departments of Chemistry and Biomedical Engineering, Metcalf Center for Science and Engineering, Boston University, Boston, MA 02215, USA; Department of Ophthalmology, Duke University Medical Center, Durham, NC 27710, USA aut Pure and Applied Chemistry De Gruyter 76/7-8(2004-01-01), 1375-1385 0033-4545 76:7-8<1375 2004 76 pac https://doi.org/10.1351/pac200476071375 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1351/pac200476071375 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Luman N. R. Departments of Chemistry and Biomedical Engineering, Metcalf Center for Science and Engineering, Boston University, Boston, MA 02215, USA; Department of Ophthalmology, Duke University Medical Center, Durham, NC 27710, USA aut NATIONALLICENCE 700 1- Kim Terry Departments of Chemistry and Biomedical Engineering, Metcalf Center for Science and Engineering, Boston University, Boston, MA 02215, USA; Department of Ophthalmology, Duke University Medical Center, Durham, NC 27710, USA aut NATIONALLICENCE 700 1- Grinstaff M. W. Departments of Chemistry and Biomedical Engineering, Metcalf Center for Science and Engineering, Boston University, Boston, MA 02215, USA; Department of Ophthalmology, Duke University Medical Center, Durham, NC 27710, USA aut NATIONALLICENCE 773 0- Pure and Applied Chemistry De Gruyter 76/7-8(2004-01-01), 1375-1385 0033-4545 76:7-8<1375 2004 76 pac CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter