Ribozymes that use redox cofactors
| LEADER | caa a22 4500 | ||
|---|---|---|---|
| 001 | 37892186X | ||
| 003 | CHVBK | ||
| 005 | 20180305123607.0 | ||
| 007 | cr unu---uuuuu | ||
| 008 | 161128e20040101xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.1351/pac200476071525 |2 doi |
| 035 | |a (NATIONALLICENCE)gruyter-10.1351/pac200476071525 | ||
| 245 | 0 | 0 | |a Ribozymes that use redox cofactors |h [Elektronische Daten] |c [S. Tsukiji, K. Ramaswamy, H. Suga] |
| 520 | 3 | |a This review summarizes the history and most recent advances in aptamers and ribozymes that bind and use redox (reduction-oxidation) cofactors. Redox reactions, catalyzed by protein enzymes in an extant world, play a central role in the metabolism of numerous biological molecules in the living organisms. The burden of catalyzing these reactions in a pre-protein-based world (i.e., the hypothesized RNA World) could have been borne by RNA molecules. To this end, we raise a fundamental question: can RNA accelerate the redox chemical transformation? We hope that this article will be able to shed light on this intriguing question. | |
| 540 | |a © 2013 Walter de Gruyter GmbH, Berlin/Boston | ||
| 700 | 1 | |a Tsukiji |D S. |u Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo 113-8656, Japan; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY 14260-3000, USA; Department of Biological Sciences, University at Buffalo, The State University of New York, Buffalo, NY 14260-3000, USA; Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo 153-8904, Japan |4 aut | |
| 700 | 1 | |a Ramaswamy |D K. |u Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo 113-8656, Japan; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY 14260-3000, USA; Department of Biological Sciences, University at Buffalo, The State University of New York, Buffalo, NY 14260-3000, USA; Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo 153-8904, Japan |4 aut | |
| 700 | 1 | |a Suga |D H. |u Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo 113-8656, Japan; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY 14260-3000, USA; Department of Biological Sciences, University at Buffalo, The State University of New York, Buffalo, NY 14260-3000, USA; Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo 153-8904, Japan |4 aut | |
| 773 | 0 | |t Pure and Applied Chemistry |d De Gruyter |g 76/7-8(2004-01-01), 1525-1536 |x 0033-4545 |q 76:7-8<1525 |1 2004 |2 76 |o pac | |
| 856 | 4 | 0 | |u https://doi.org/10.1351/pac200476071525 |q text/html |z Onlinezugriff via DOI |
| 908 | |D 1 |a research article |2 jats | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1351/pac200476071525 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Tsukiji |D S. |u Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo 113-8656, Japan; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY 14260-3000, USA; Department of Biological Sciences, University at Buffalo, The State University of New York, Buffalo, NY 14260-3000, USA; Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo 153-8904, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ramaswamy |D K. |u Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo 113-8656, Japan; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY 14260-3000, USA; Department of Biological Sciences, University at Buffalo, The State University of New York, Buffalo, NY 14260-3000, USA; Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo 153-8904, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Suga |D H. |u Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo 113-8656, Japan; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY 14260-3000, USA; Department of Biological Sciences, University at Buffalo, The State University of New York, Buffalo, NY 14260-3000, USA; Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo 153-8904, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Pure and Applied Chemistry |d De Gruyter |g 76/7-8(2004-01-01), 1525-1536 |x 0033-4545 |q 76:7-8<1525 |1 2004 |2 76 |o pac | ||
| 900 | 7 | |b CC0 |u http://creativecommons.org/publicdomain/zero/1.0 |2 nationallicence | |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-gruyter | ||