PLS Dimension Reduction for Classification with Microarray Data

Verfasser / Beitragende:
[Anne-Laure Boulesteix]
Ort, Verlag, Jahr:
2004
Enthalten in:
Statistical Applications in Genetics and Molecular Biology, 3/1(2004-11-23), 1-30
Format:
Artikel (online)
ID: 378925830
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024 7 0 |a 10.2202/1544-6115.1075  |2 doi 
035 |a (NATIONALLICENCE)gruyter-10.2202/1544-6115.1075 
100 1 |a Boulesteix  |D Anne-Laure  |u Department of Statistics, University of Munich 
245 1 0 |a PLS Dimension Reduction for Classification with Microarray Data  |h [Elektronische Daten]  |c [Anne-Laure Boulesteix] 
520 3 |a Partial Least Squares (PLS) dimension reduction is known to give good prediction accuracy in the context of classification with high-dimensional microarray data. In this paper, the classification procedure consisting of PLS dimension reduction and linear discriminant analysis on the new components is compared with some of the best state-of-the-art classification methods. Moreover, a boosting algorithm is applied to this classification method. In addition, a simple procedure to choose the number of PLS components is suggested. The connection between PLS dimension reduction and gene selection is examined and a property of the first PLS component for binary classification is proved. In addition, we show how PLS can be used for data visualization using real data. The whole study is based on 9 real microarray cancer data sets. 
540 |a ©2011 Walter de Gruyter GmbH & Co. KG, Berlin/Boston 
690 7 |a Microarrays  |2 nationallicence 
690 7 |a Multivariate Analysis  |2 nationallicence 
690 7 |a partial least squares  |2 nationallicence 
690 7 |a feature extraction  |2 nationallicence 
690 7 |a variable selection  |2 nationallicence 
690 7 |a boosting  |2 nationallicence 
690 7 |a gene expression  |2 nationallicence 
690 7 |a discriminant analysis  |2 nationallicence 
690 7 |a supervised learning  |2 nationallicence 
773 0 |t Statistical Applications in Genetics and Molecular Biology  |d De Gruyter  |g 3/1(2004-11-23), 1-30  |q 3:1<1  |1 2004  |2 3  |o sagmb 
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950 |B NATIONALLICENCE  |P 100  |E 1-  |a Boulesteix  |D Anne-Laure  |u Department of Statistics, University of Munich 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Statistical Applications in Genetics and Molecular Biology  |d De Gruyter  |g 3/1(2004-11-23), 1-30  |q 3:1<1  |1 2004  |2 3  |o sagmb 
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