caa a22 4500 378931601 CHVBK 20180305123631.0 cr unu---uuuuu 161128e20040101xx s 000 0 eng 10.1351/pac200476040789 doi (NATIONALLICENCE)gruyter-10.1351/pac200476040789 Electrochemistry and application of a novel monosubstituted squarate electron-transfer mediator in a glucose oxidase-doped poly(phenol) sensor [Elektronische Daten] [E. I. Iwuoha, A. R. Williams-Dottin, L. A. Hall, A. Morrin, G. N. Mathebe, M. R. Smyth, Anthony Killard] Electrosynthetic poly(phenol) nanofilms were deposited in situ on platinum electrodes in the presence and absence of glucose oxidase. The synthesis charges and currents of the nonconducting polymer films were recorded at various applied potentials for films grown from 25 -100 mM phenol concentrations. Film parameters such as the standard rate constant for film deposition, film thickness, and surface concentration of the poly(phenol) films were evaluated from the cyclic and step voltammograms of the polymerization process. A novel electron-transfer mediator consisting of monosubstituted 4-hydroxycyclobut-3-ene-1,2-dione (squarate) was used as a mediator for Pt/poly(phenol) nanofilm/GOx amperometric glucose biosensors. Amperometric responses for 3-diphenylamino-4-hydroxycyclobut-3-ene-1,2-dione (diphenylaminosquarate: E°'=of +328 mV/Ag-AgCl at pH 7.0)-mediated systems were measured by both steady-state amperometric and cyclic voltammetry. The sensor sensitivity was calculated to be 558 nA cm−2 (µM)−1. © 2013 Walter de Gruyter GmbH, Berlin/Boston Iwuoha E. I. Department of Chemistry, University of the Western Cape, Belleville 7535, South Africa; Department of Chemistry, The University of the West Indies, St.Augustine, Trinidad; School of Chemical Sciences, Dublin City University, Dublin 9, Ireland aut Williams-Dottin A. R. Department of Chemistry, University of the Western Cape, Belleville 7535, South Africa; Department of Chemistry, The University of the West Indies, St.Augustine, Trinidad; School of Chemical Sciences, Dublin City University, Dublin 9, Ireland aut Hall L. A. Department of Chemistry, University of the Western Cape, Belleville 7535, South Africa; Department of Chemistry, The University of the West Indies, St.Augustine, Trinidad; School of Chemical Sciences, Dublin City University, Dublin 9, Ireland aut Morrin A. Department of Chemistry, University of the Western Cape, Belleville 7535, South Africa; Department of Chemistry, The University of the West Indies, St.Augustine, Trinidad; School of Chemical Sciences, Dublin City University, Dublin 9, Ireland aut Mathebe G. N. Department of Chemistry, University of the Western Cape, Belleville 7535, South Africa; Department of Chemistry, The University of the West Indies, St.Augustine, Trinidad; School of Chemical Sciences, Dublin City University, Dublin 9, Ireland aut Smyth M. R. Department of Chemistry, University of the Western Cape, Belleville 7535, South Africa; Department of Chemistry, The University of the West Indies, St.Augustine, Trinidad; School of Chemical Sciences, Dublin City University, Dublin 9, Ireland aut Killard Anthony Department of Chemistry, University of the Western Cape, Belleville 7535, South Africa; Department of Chemistry, The University of the West Indies, St.Augustine, Trinidad; School of Chemical Sciences, Dublin City University, Dublin 9, Ireland aut Pure and Applied Chemistry De Gruyter 76/4(2004-01-01), 789-799 0033-4545 76:4<789 2004 76 pac https://doi.org/10.1351/pac200476040789 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1351/pac200476040789 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Iwuoha E. I. Department of Chemistry, University of the Western Cape, Belleville 7535, South Africa; Department of Chemistry, The University of the West Indies, St.Augustine, Trinidad; School of Chemical Sciences, Dublin City University, Dublin 9, Ireland aut NATIONALLICENCE 700 1- Williams-Dottin A. R. Department of Chemistry, University of the Western Cape, Belleville 7535, South Africa; Department of Chemistry, The University of the West Indies, St.Augustine, Trinidad; School of Chemical Sciences, Dublin City University, Dublin 9, Ireland aut NATIONALLICENCE 700 1- Hall L. A. Department of Chemistry, University of the Western Cape, Belleville 7535, South Africa; Department of Chemistry, The University of the West Indies, St.Augustine, Trinidad; School of Chemical Sciences, Dublin City University, Dublin 9, Ireland aut NATIONALLICENCE 700 1- Morrin A. Department of Chemistry, University of the Western Cape, Belleville 7535, South Africa; Department of Chemistry, The University of the West Indies, St.Augustine, Trinidad; School of Chemical Sciences, Dublin City University, Dublin 9, Ireland aut NATIONALLICENCE 700 1- Mathebe G. N. Department of Chemistry, University of the Western Cape, Belleville 7535, South Africa; Department of Chemistry, The University of the West Indies, St.Augustine, Trinidad; School of Chemical Sciences, Dublin City University, Dublin 9, Ireland aut NATIONALLICENCE 700 1- Smyth M. R. Department of Chemistry, University of the Western Cape, Belleville 7535, South Africa; Department of Chemistry, The University of the West Indies, St.Augustine, Trinidad; School of Chemical Sciences, Dublin City University, Dublin 9, Ireland aut NATIONALLICENCE 700 1- Killard Anthony Department of Chemistry, University of the Western Cape, Belleville 7535, South Africa; Department of Chemistry, The University of the West Indies, St.Augustine, Trinidad; School of Chemical Sciences, Dublin City University, Dublin 9, Ireland aut NATIONALLICENCE 773 0- Pure and Applied Chemistry De Gruyter 76/4(2004-01-01), 789-799 0033-4545 76:4<789 2004 76 pac CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter