In situ poly(ethylene imine) coating of hollow fiber membranes used for microdialysis sampling
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| 024 | 7 | 0 | |a 10.1351/pac200476040879 |2 doi |
| 035 | |a (NATIONALLICENCE)gruyter-10.1351/pac200476040879 | ||
| 245 | 0 | 0 | |a In situ poly(ethylene imine) coating of hollow fiber membranes used for microdialysis sampling |h [Elektronische Daten] |c [N. Torto, M. Ohlrogge, L. Gorton, J. M. Van Alstine, Thomas Laurell, G. Marko-Varga] |
| 520 | 3 | |a A method for the in situ modification of hollow fiber membranes used as sampling units for microdialysis probes is presented. The method consists of adsorption-coating, high molecular-weight poly(ethylene imine), PEI, onto membranes, already fitted on microdialysis probes. Modification of membranes was designed to specifically explore the so-called Andrade effects and thus enhance the interaction of membranes with enzyme. The performances of polysulfone, polyethersulfone, and polyamide membranes modified with PEI-enzyme complex were evaluated based on the membrane extraction fraction for maltose and maltotriose and membrane morphology as examined by scanning electron microscopy. Of the membranes tested, the PEI-enzyme complex least affected the performance of the polysulfone membranes. Conversion of maltoheptaose to maltotriose and maltose was increased reproducibly (within a 5 % relative standard deviation) by 50 % for modified membranes compared to the native hollow fiber membranes. The results demonstrate the potential to effectively modify membranes already fitted on a microdialysis probe. Such a procedure can be modified and employed to either promote or reduce membrane-protein interaction for hollow fibers used as microdialysis sampling units or other similar membrane applications. | |
| 540 | |a © 2013 Walter de Gruyter GmbH, Berlin/Boston | ||
| 700 | 1 | |a Torto |D N. |u Department of Chemistry, University of Botswana, P/Bag UB 00704, Gaborone, Botswana; Department of Analytical Chemistry, University of Lund, P.O. Box 124, SE-221 00, Lund, Sweden; Department of Chemical Engineering and Technology, KET/TS, Royal Institute of Technology, SE-100 44, Stockholm, Sweden; Department of Electrical Measurements, University of Lund, P.O. Box 118, SE-221 00, Lund, Sweden; Bioanalytical Research, Astra-Zeneca, Pre-Clinical Research and Development, P.O.Box 34, SE-221 00, Lund, Sweden |4 aut | |
| 700 | 1 | |a Ohlrogge |D M. |u Department of Chemistry, University of Botswana, P/Bag UB 00704, Gaborone, Botswana; Department of Analytical Chemistry, University of Lund, P.O. Box 124, SE-221 00, Lund, Sweden; Department of Chemical Engineering and Technology, KET/TS, Royal Institute of Technology, SE-100 44, Stockholm, Sweden; Department of Electrical Measurements, University of Lund, P.O. Box 118, SE-221 00, Lund, Sweden; Bioanalytical Research, Astra-Zeneca, Pre-Clinical Research and Development, P.O.Box 34, SE-221 00, Lund, Sweden |4 aut | |
| 700 | 1 | |a Gorton |D L. |u Department of Chemistry, University of Botswana, P/Bag UB 00704, Gaborone, Botswana; Department of Analytical Chemistry, University of Lund, P.O. Box 124, SE-221 00, Lund, Sweden; Department of Chemical Engineering and Technology, KET/TS, Royal Institute of Technology, SE-100 44, Stockholm, Sweden; Department of Electrical Measurements, University of Lund, P.O. Box 118, SE-221 00, Lund, Sweden; Bioanalytical Research, Astra-Zeneca, Pre-Clinical Research and Development, P.O.Box 34, SE-221 00, Lund, Sweden |4 aut | |
| 700 | 1 | |a Van Alstine |D J. M. |u Department of Chemistry, University of Botswana, P/Bag UB 00704, Gaborone, Botswana; Department of Analytical Chemistry, University of Lund, P.O. Box 124, SE-221 00, Lund, Sweden; Department of Chemical Engineering and Technology, KET/TS, Royal Institute of Technology, SE-100 44, Stockholm, Sweden; Department of Electrical Measurements, University of Lund, P.O. Box 118, SE-221 00, Lund, Sweden; Bioanalytical Research, Astra-Zeneca, Pre-Clinical Research and Development, P.O.Box 34, SE-221 00, Lund, Sweden |4 aut | |
| 700 | 1 | |a Laurell |D Thomas |u Department of Chemistry, University of Botswana, P/Bag UB 00704, Gaborone, Botswana; Department of Analytical Chemistry, University of Lund, P.O. Box 124, SE-221 00, Lund, Sweden; Department of Chemical Engineering and Technology, KET/TS, Royal Institute of Technology, SE-100 44, Stockholm, Sweden; Department of Electrical Measurements, University of Lund, P.O. Box 118, SE-221 00, Lund, Sweden; Bioanalytical Research, Astra-Zeneca, Pre-Clinical Research and Development, P.O.Box 34, SE-221 00, Lund, Sweden |4 aut | |
| 700 | 1 | |a Marko-Varga |D G. |u Department of Chemistry, University of Botswana, P/Bag UB 00704, Gaborone, Botswana; Department of Analytical Chemistry, University of Lund, P.O. Box 124, SE-221 00, Lund, Sweden; Department of Chemical Engineering and Technology, KET/TS, Royal Institute of Technology, SE-100 44, Stockholm, Sweden; Department of Electrical Measurements, University of Lund, P.O. Box 118, SE-221 00, Lund, Sweden; Bioanalytical Research, Astra-Zeneca, Pre-Clinical Research and Development, P.O.Box 34, SE-221 00, Lund, Sweden |4 aut | |
| 773 | 0 | |t Pure and Applied Chemistry |d De Gruyter |g 76/4(2004-01-01), 879-888 |x 0033-4545 |q 76:4<879 |1 2004 |2 76 |o pac | |
| 856 | 4 | 0 | |u https://doi.org/10.1351/pac200476040879 |q text/html |z Onlinezugriff via DOI |
| 908 | |D 1 |a research article |2 jats | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1351/pac200476040879 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Torto |D N. |u Department of Chemistry, University of Botswana, P/Bag UB 00704, Gaborone, Botswana; Department of Analytical Chemistry, University of Lund, P.O. Box 124, SE-221 00, Lund, Sweden; Department of Chemical Engineering and Technology, KET/TS, Royal Institute of Technology, SE-100 44, Stockholm, Sweden; Department of Electrical Measurements, University of Lund, P.O. Box 118, SE-221 00, Lund, Sweden; Bioanalytical Research, Astra-Zeneca, Pre-Clinical Research and Development, P.O.Box 34, SE-221 00, Lund, Sweden |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ohlrogge |D M. |u Department of Chemistry, University of Botswana, P/Bag UB 00704, Gaborone, Botswana; Department of Analytical Chemistry, University of Lund, P.O. Box 124, SE-221 00, Lund, Sweden; Department of Chemical Engineering and Technology, KET/TS, Royal Institute of Technology, SE-100 44, Stockholm, Sweden; Department of Electrical Measurements, University of Lund, P.O. Box 118, SE-221 00, Lund, Sweden; Bioanalytical Research, Astra-Zeneca, Pre-Clinical Research and Development, P.O.Box 34, SE-221 00, Lund, Sweden |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Gorton |D L. |u Department of Chemistry, University of Botswana, P/Bag UB 00704, Gaborone, Botswana; Department of Analytical Chemistry, University of Lund, P.O. Box 124, SE-221 00, Lund, Sweden; Department of Chemical Engineering and Technology, KET/TS, Royal Institute of Technology, SE-100 44, Stockholm, Sweden; Department of Electrical Measurements, University of Lund, P.O. Box 118, SE-221 00, Lund, Sweden; Bioanalytical Research, Astra-Zeneca, Pre-Clinical Research and Development, P.O.Box 34, SE-221 00, Lund, Sweden |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Van Alstine |D J. M. |u Department of Chemistry, University of Botswana, P/Bag UB 00704, Gaborone, Botswana; Department of Analytical Chemistry, University of Lund, P.O. Box 124, SE-221 00, Lund, Sweden; Department of Chemical Engineering and Technology, KET/TS, Royal Institute of Technology, SE-100 44, Stockholm, Sweden; Department of Electrical Measurements, University of Lund, P.O. Box 118, SE-221 00, Lund, Sweden; Bioanalytical Research, Astra-Zeneca, Pre-Clinical Research and Development, P.O.Box 34, SE-221 00, Lund, Sweden |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Laurell |D Thomas |u Department of Chemistry, University of Botswana, P/Bag UB 00704, Gaborone, Botswana; Department of Analytical Chemistry, University of Lund, P.O. Box 124, SE-221 00, Lund, Sweden; Department of Chemical Engineering and Technology, KET/TS, Royal Institute of Technology, SE-100 44, Stockholm, Sweden; Department of Electrical Measurements, University of Lund, P.O. Box 118, SE-221 00, Lund, Sweden; Bioanalytical Research, Astra-Zeneca, Pre-Clinical Research and Development, P.O.Box 34, SE-221 00, Lund, Sweden |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Marko-Varga |D G. |u Department of Chemistry, University of Botswana, P/Bag UB 00704, Gaborone, Botswana; Department of Analytical Chemistry, University of Lund, P.O. Box 124, SE-221 00, Lund, Sweden; Department of Chemical Engineering and Technology, KET/TS, Royal Institute of Technology, SE-100 44, Stockholm, Sweden; Department of Electrical Measurements, University of Lund, P.O. Box 118, SE-221 00, Lund, Sweden; Bioanalytical Research, Astra-Zeneca, Pre-Clinical Research and Development, P.O.Box 34, SE-221 00, Lund, Sweden |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Pure and Applied Chemistry |d De Gruyter |g 76/4(2004-01-01), 879-888 |x 0033-4545 |q 76:4<879 |1 2004 |2 76 |o pac | ||
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