caa a22 4500 378937960 CHVBK 20180305123645.0 cr unu---uuuuu 161128e20040709xx s 000 0 eng 10.1515/JPM.2004.064 doi (NATIONALLICENCE)gruyter-10.1515/JPM.2004.064 Different maternal serum hCG levels in pregnant women with female and male fetuses: does fetal hypophyseal - adrenal - gonadal axis play a role? [Elektronische Daten] [M. Gol, S. Altunyurt, D. Cimrin, S. Guclu, M. Bagci, N. Demir] Fetal gender has a significant effect on maternal and cord blood hCG levels, particularly during the last trimester of the pregnancy. However, the reason for this difference is obscure. The aim of the present study was to investigate whether term fetal hypophyseal - adrenal - gonadal axis differs between female and male fetuses thereby causing different hCG levels. The study consisted of 60 women with singleton pregnancies in the third trimester. Thirtyone pregnant women were carrying female fetuses, whereas 29 were carrying male. Human chorionic gonadotropin (hCG), estradiol, progesterone, testosterone, dehydro-epiandrosteron-sulfate (DHEAS), prolactin and growth hormone levels were measured in maternal serum and umbilical cord blood. In female bearing pregnancies maternal and cord blood hCG levels were significantly higher than in male bearing pregnancies (P<0.001). Maternal and cord blood estradiol, progesterone, testosterone, DHEAS, prolactin and growth hormone levels were not significantly different in either fetal gender. When all patients were considered as a group there were no correlations between fetal hCG levels and any of the measured hormones. Term fetal DHEAS, estrogen, progesterone, testosterone, growth hormone and prolactin levels do not contribute to different hCG levels between female and male fetuses. It is possible that fetal hypophyseal-adrenal - gonadal axis does not play a central role as the cause of different hCG levels. Copyright © 2004 by Walter de Gruyter GmbH & Co. KG Human reproduction, growth & development nationallicence Gynaecology & obstetrics nationallicence Paediatric medicine nationallicence Gol M. aut Altunyurt S. aut Cimrin D. aut Guclu S. aut Bagci M. aut Demir N. aut Journal of Perinatal Medicine Walter de Gruyter 32/4(2004-07-09), 342-345 0300-5577 32:4<342 2004 32 jpme https://doi.org/10.1515/JPM.2004.064 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1515/JPM.2004.064 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gol M. aut NATIONALLICENCE 700 1- Altunyurt S. aut NATIONALLICENCE 700 1- Cimrin D. aut NATIONALLICENCE 700 1- Guclu S. aut NATIONALLICENCE 700 1- Bagci M. aut NATIONALLICENCE 700 1- Demir N. aut NATIONALLICENCE 773 0- Journal of Perinatal Medicine Walter de Gruyter 32/4(2004-07-09), 342-345 0300-5577 32:4<342 2004 32 jpme CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter