caa a22 4500 378941054 CHVBK 20180305123652.0 cr unu---uuuuu 161128e20041001xx s 000 0 eng 10.1515/BC.2004.121 doi (NATIONALLICENCE)gruyter-10.1515/BC.2004.121 How do ABC transporters drive transport? [Elektronische Daten] [Chris Van Der Does, Robert Tampé] Members of the ATP-binding cassette (ABC) superfamily are integral membrane proteins that hydrolyze ATP to drive transport. In the last two decades these proteins have been extensively characterized on a genetic and biochemical level, and in recent years high-resolution crystal structures of several nucleotide-binding domains and full-length transporters have extended our knowledge. Here we discuss the possible mechanisms of transport that have been derived from these crystal structures and the extensive available biochemical data. © Walter de Gruyter Biochemistry nationallicence Molecular biology nationallicence Cellular biology nationallicence ATP-binding cassette proteins nationallicence membrane proteins nationallicence nucleotide-binding proteins nationallicence structure nationallicence transport ATPases nationallicence transport mechanism nationallicence Van Der Does Chris Institute of Biochemistry, Biozentrum Frankfurt, Johann Wolfgang Goethe-University, Marie-Curie-Str. 9, D-60439 Frankfurt/Main, Germany aut Tampé Robert Institute of Biochemistry, Biozentrum Frankfurt, Johann Wolfgang Goethe-University, Marie-Curie-Str. 9, D-60439 Frankfurt/Main, Germany aut Biological Chemistry Walter de Gruyter 385/10(2004-10-01), 927-933 1431-6730 385:10<927 2004 385 bchm https://doi.org/10.1515/BC.2004.121 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1515/BC.2004.121 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Van Der Does Chris Institute of Biochemistry, Biozentrum Frankfurt, Johann Wolfgang Goethe-University, Marie-Curie-Str. 9, D-60439 Frankfurt/Main, Germany aut NATIONALLICENCE 700 1- Tampé Robert Institute of Biochemistry, Biozentrum Frankfurt, Johann Wolfgang Goethe-University, Marie-Curie-Str. 9, D-60439 Frankfurt/Main, Germany aut NATIONALLICENCE 773 0- Biological Chemistry Walter de Gruyter 385/10(2004-10-01), 927-933 1431-6730 385:10<927 2004 385 bchm CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter