caa a22 4500 378942387 CHVBK 20180305123655.0 cr unu---uuuuu 161128e20040315xx s 000 0 eng 10.1515/JPM.2004.030 doi (NATIONALLICENCE)gruyter-10.1515/JPM.2004.030 Clinical characteristics and follow up of Down syndrome infants without congenital heart disease who presented with persistent pulmonary hypertension of newborn [Elektronische Daten] [P. S. Shah, J. Hellmann, I. Adatia] We identified seventeen infants with Down syndrome without structural congenital heart disease who presented with persistent pulmonary hypertension in the newborn period. Respiratory distress with or without hypoxia was the presenting feature in these infants. Pulmonary hypertension resolved in the majority of the survivors. Two infants with refractory pulmonary hypertension benefited from patent ductus arteriosus ligation. Autopsies in two infants demonstrated structural lung immaturity. We suggest that infants with Down syndrome are at risk of developing persistent pulmonary hypertension even in the absence of structural heart disease and these infants should be followed up until resolution of the pulmonary hypertension. Copyright © 2004 by Walter de Gruyter GmbH & Co. KG Human reproduction, growth & development nationallicence Gynaecology & obstetrics nationallicence Paediatric medicine nationallicence Shah P. S. aut Hellmann J. aut Adatia I. aut Journal of Perinatal Medicine Walter de Gruyter 32/2(2004-03-15), 168-170 0300-5577 32:2<168 2004 32 jpme https://doi.org/10.1515/JPM.2004.030 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1515/JPM.2004.030 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Shah P. S. aut NATIONALLICENCE 700 1- Hellmann J. aut NATIONALLICENCE 700 1- Adatia I. aut NATIONALLICENCE 773 0- Journal of Perinatal Medicine Walter de Gruyter 32/2(2004-03-15), 168-170 0300-5577 32:2<168 2004 32 jpme CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter