caa a22 4500 378942425 CHVBK 20180305123655.0 cr unu---uuuuu 161128e20040301xx s 000 0 eng 10.1515/JPM.2004.027 doi (NATIONALLICENCE)gruyter-10.1515/JPM.2004.027 The association of birthweight with maternal and cord serum and amniotic fluid growth hormone and insulin levels, and with neonatal and maternal factors in pregnant women who delivered at term [Elektronische Daten] [Mehmet A. Osmanağaoğlu, Selen Osmanağaoğlu, Hasan Bozkaya] Aim: To investigate the influence of maternal and cord serum and amniotic fluid growth hormone (GH) and insulin and other neonatal and maternal factors on birthweight. Methods: A total of 160 pregnant women at 38-42 weeks' gestation were studied. All infants were categorized as small for gestational age (SGA) (n = 50), large for gestational age (LGA) (n = 50) or average for gestational age (AGA) (n = 60). GH and insulin levels were measured in maternal and cord serum and amniotic fluid at birth. Results: GH levels in maternal and cord serum and amniotic fluid showed no differences among the three weight groups (P > 0.05). The cord insulin level was significantly lower in SGA (P < 0.01). The insulin level in venous cord blood correlated with birth and placental weights and neonatal height, whereas maternal serum and amniotic fluid insulin levels, and maternal and cord serum and amniotic fluid GH levels did not show any correlation with birthweight. The cord GH level at birth was correlated with GH levels after 4 postnatal weeks in the SGA group (P < 0.01). In addition, birthweight showed a correlation with prepartum maternal weight, maternal weight gain, maternal height, neonatal length and placental weight in all three weight groups. Conclusions: Cord GH, maternal serum and amniotic fluid GH and insulin levels did not correlate with birthweight in all three weight groups. The lack of correlation for GH levels in maternal and cord serum and amniotic fluid suggests that these compartments may be noncommunicating separate units. © Walter de Gruyter Human reproduction, growth & development nationallicence Gynaecology & obstetrics nationallicence Paediatric medicine nationallicence Birthweight nationallicence gender nationallicence growth hormone nationallicence insulin nationallicence maternal and neonatal factors nationallicence Osmanağaoğlu Mehmet A. Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey. aut Osmanağaoğlu Selen Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey. aut Bozkaya Hasan Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey. aut Journal of Perinatal Medicine Walter de Gruyter 32/2(2004-03-01), 149-155 0300-5577 32:2<149 2004 32 jpme https://doi.org/10.1515/JPM.2004.027 text/html Onlinezugriff via DOI 1 research article jats NATIONALLICENCE 856 40 https://doi.org/10.1515/JPM.2004.027 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Osmanağaoğlu Mehmet A. Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey aut NATIONALLICENCE 700 1- Osmanağaoğlu Selen Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey aut NATIONALLICENCE 700 1- Bozkaya Hasan Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey aut NATIONALLICENCE 773 0- Journal of Perinatal Medicine Walter de Gruyter 32/2(2004-03-01), 149-155 0300-5577 32:2<149 2004 32 jpme CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence SWISSBIB 378942425 BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-gruyter