caa a22 4500 386322074 CHVBK 20180307111630.0 cr unu---uuuuu 161130e198807 xx s 000 0 eng 10.1079/BJN19880082 doi S0007114588000832 pii (NATIONALLICENCE)cambridge-10.1079/BJN19880082 Amino acid absorption and production of pancreatic hormones in non-anaesthetized pigs after duodenal infusions of a milk enzymic hydrolysate or of free amino acids [Elektronische Daten] 1. Six non-anaesthetized pigs (mean body-weight 57.0 kg) were used to study the intestinal absorption of amino acids (AA) from either an enzymic hydrolysate of milk (PEP) containing a large percentage of small peptides (about 50% with less than five AA residues) and very few free AA (8%), or from a mixture of free AA with an identical pattern (AAL) infused intraduodenally in one of two amounts (55 or 110 g). Concomitant insulin and glucagon production rates were estimated. 2. Each pig was previously fitted, under anaesthesia, with an electromagnetic flow probe. around the portal vein, with permanent catheters in the portal vein, the carotid artery and the duodenum. Each infusion was performed after an 18 h fasting period and each pig received each infusion. The observation period lasted for 5 h. 3. The absorption of AA was greater, more rapid and more homogeneous after PEP infusion than after AAL infusion, independent of the amount infused. 4. For the majority of AA considered individually, the absorption coefficient was higher after infusion of PEP than after that of AAL. The exceptions were methionine with a higher absorption coefficient after AAL infusion, and isoleucine, aspartic acid + asparagine and glutamic acid + glutamine with identical coefficients for both infusions. 5. Some AA, such as asparagine, ornithine, citrulline and taurine, while absent in the infusates, appeared in the portal vein in appreciable amounts after the infusion of both solutions. While a small proportion of taurine may arise from recycling of taurine-containing bile salts, it seems that the gut wall is able to synthesize all four AA. 6. Insulin production did not differ according to the nature or amount of solutions infused. Glucagon production was greater after PEP infusion. Copyright © The Nutrition Society 1988 Rérat A. Laboratoire de Physiologie de la Nutrition, INRA, Centre de Recherches de Jouy-en-Josas, 78350 Jouy-en-Josas, France Nunes C. Simoes Laboratoire de Physiologie de la Nutrition, INRA, Centre de Recherches de Jouy-en-Josas, 78350 Jouy-en-Josas, France Mendy F. Laboratoire Sopharga, 5 Rue Bellini, 92806 Puteaux, France Roger L. Laboratoire Sopharga, 5 Rue Bellini, 92806 Puteaux, France British Journal of Nutrition Cambridge University Press 60/1(1988-07), 121-136 0007-1145 60:1<121 1988 60 BJN https://doi.org/10.1079/BJN19880082 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1079/BJN19880082 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Rérat A. Laboratoire de Physiologie de la Nutrition, INRA, Centre de Recherches de Jouy-en-Josas, 78350 Jouy-en-Josas, France NATIONALLICENCE 700 1- Nunes C. Simoes Laboratoire de Physiologie de la Nutrition, INRA, Centre de Recherches de Jouy-en-Josas, 78350 Jouy-en-Josas, France NATIONALLICENCE 700 1- Mendy F. Laboratoire Sopharga, 5 Rue Bellini, 92806 Puteaux, France NATIONALLICENCE 700 1- Roger L. Laboratoire Sopharga, 5 Rue Bellini, 92806 Puteaux, France NATIONALLICENCE 773 0- British Journal of Nutrition Cambridge University Press 60/1(1988-07), 121-136 0007-1145 60:1<121 1988 60 BJN CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge