caa a22 4500 386322155 CHVBK 20180307111630.0 cr unu---uuuuu 161130e198807 xx s 000 0 eng 10.1079/BJN19880078 doi S0007114588000790 pii (NATIONALLICENCE)cambridge-10.1079/BJN19880078 Contribution of liver, skin and skeletal muscle to whole-body protein synthesis in the young lamb [Elektronische Daten] 1. Protein fractional synthesis rate (FSR) was measured in some major tissues and in the whole body of six 1-week-old sucking lambs by a large injection of L-[3H]valine. 2. Upper estimates of tissue protein FSR (%/d), assuming that the tissue-homogenate free-valine specific radioactivity defined that of valyl tRNA, were 115.0 in liver, 24.1 in skin, 22.9 in the white M. tensor fasciae latae, 21.6 in the red M. diaphragma and 19-6 in the remainder (exsanguinated whole body without liver and gastrointestinal tract) of lambs. 3. Absolute synthesis rates (ASR) of tissue protein were 17, 19 and 42 g/d in the liver, skin and skeletal muscle respectively, and 112 g/d in the remainder. The ASR of whole-body protein, derived from the tissue values, was 146 g/d, i.e. 33 g/d per kg body-weight. The calculated whole-body protein FSR was 23.9 %/d. 4. The relative percentage contribution of liver, skin and skeletal muscle to whole-body protein synthesis was 11.7, 13.1, and 29.0. 5. We concluded that tissue protein FSR in lambs were in exactly the same decreasing order, from visceral tissues to skeletal muscles, as observed in rats. The ovine FSR estimates and the partitioning of protein synthesis between tissues were in the same range as values recently obtained by flooding-dose experiments in immature rats, piglets, and even in chicks. These findings suggest that inter-species differences are rather limited. Copyright © The Nutrition Society 1988 Attaix D. INRA et CNRS U.A. 1123, Centre de Recherches Zootechniques et Vétérinaires de Theix, 63122 Ceyrat, France Aurousseau E. INRA et CNRS U.A. 1123, Centre de Recherches Zootechniques et Vétérinaires de Theix, 63122 Ceyrat, France Manghebati A. INRA et CNRS U.A. 1123, Centre de Recherches Zootechniques et Vétérinaires de Theix, 63122 Ceyrat, France Arnal M. INRA et CNRS U.A. 1123, Centre de Recherches Zootechniques et Vétérinaires de Theix, 63122 Ceyrat, France British Journal of Nutrition Cambridge University Press 60/1(1988-07), 77-84 0007-1145 60:1<77 1988 60 BJN https://doi.org/10.1079/BJN19880078 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1079/BJN19880078 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Attaix D. INRA et CNRS U.A. 1123, Centre de Recherches Zootechniques et Vétérinaires de Theix, 63122 Ceyrat, France NATIONALLICENCE 700 1- Aurousseau E. INRA et CNRS U.A. 1123, Centre de Recherches Zootechniques et Vétérinaires de Theix, 63122 Ceyrat, France NATIONALLICENCE 700 1- Manghebati A. INRA et CNRS U.A. 1123, Centre de Recherches Zootechniques et Vétérinaires de Theix, 63122 Ceyrat, France NATIONALLICENCE 700 1- Arnal M. INRA et CNRS U.A. 1123, Centre de Recherches Zootechniques et Vétérinaires de Theix, 63122 Ceyrat, France NATIONALLICENCE 773 0- British Journal of Nutrition Cambridge University Press 60/1(1988-07), 77-84 0007-1145 60:1<77 1988 60 BJN CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge