caa a22 4500 386322171 CHVBK 20180307111630.0 cr unu---uuuuu 161130e198807 xx s 000 0 eng 10.1079/BJN19880074 doi S0007114588000753 pii (NATIONALLICENCE)cambridge-10.1079/BJN19880074 The effect of underfeeding on the physiological response to food ingestion in normal weight women [Elektronische Daten] 1. The thermogenic, cardiovascular and metabolic responses to the ingestion of a 30 kJ/kg body-weight test meal were studied in six normal weight, female subjects before and after a 7 d period of underfeeding at 60 kJ/ kg ideal body-weight per d. 2. With underfeeding there were decreases in body-weight, plasma insulin and 3,5,3'-triiodothyronine concentrations, resting metabolic rate and respiratory exchange ratio, with increased blood ketone levels. Baseline ‘arterialized' venous plasma noradrenaline and adrenaline concentrations were not affected by underfeeding. 3. Ingestion of the test meal caused similar increases in heart rate and calf blood flow and changes in blood pressure in the fed and underfed states. There was a greater glycaemic response to the test meal in the underfed state compared with the fed state although the rise in plasma insulin concentration was similar and ketogenesis was suppressed. The increases in metabolic rate and plasma noradrenaline concentrations following the test meal were similar in the fed and underfed states. 4. Although the period of underfeeding in the present study led to considerable metabolic adaptation, and some alteration in physiological responses to ingestion of a test meal, there was no evidence that there were associated changes in sympathetic nervous system activation. Copyright © The Nutrition Society 1988 Mansell P. I. Department of Physiology and Pharmacology, Medical School, Queen's Medical Centre, Nottingham NG7 2UH Macdonald I. A. Department of Physiology and Pharmacology, Medical School, Queen's Medical Centre, Nottingham NG7 2UH British Journal of Nutrition Cambridge University Press 60/1(1988-07), 39-48 0007-1145 60:1<39 1988 60 BJN https://doi.org/10.1079/BJN19880074 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1079/BJN19880074 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Mansell P. I. Department of Physiology and Pharmacology, Medical School, Queen's Medical Centre, Nottingham NG7 2UH NATIONALLICENCE 700 1- Macdonald I. A. Department of Physiology and Pharmacology, Medical School, Queen's Medical Centre, Nottingham NG7 2UH NATIONALLICENCE 773 0- British Journal of Nutrition Cambridge University Press 60/1(1988-07), 39-48 0007-1145 60:1<39 1988 60 BJN CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge