caa a22 4500 386322570 CHVBK 20180307111632.0 cr unu---uuuuu 161130e198809 xx s 000 0 eng 10.1079/BJN19880092 doi S0007114588000935 pii (NATIONALLICENCE)cambridge-10.1079/BJN19880092 The effect of alcoholic beverages on iron and zinc metabolism in the rat [Elektronische Daten] 1. Male Wistar rats (approximately 200 g) were given distilled water and a semi-synthetic control diet for 6 d. On day 7, 37 kBq 65Zn were administered intramuscularly and the rats were given distilled water, beer, cider, red wine, whisky or ethanol as their only source of fluid. The wine, whisky and ethanol were diluted so that each of the beverages contained a similar ethanol concentration (approximately 30 g/1). Food and fluid intake, growth rate and whole-body 65Zn were measured regularly over 11 d, after which animals were killed and blood haemoglobin (Hb) concentration, liver iron stores and the Zn concentration in testes determined. 2. There were no differences in body-weight gain or food intake between groups but fluid intake for the beer group was considerably higher than that for the other groups. 3. There was a significant effect of the type of alcoholic beverage consumed on whole-body 65Zn retention. Rats given whisky had a smaller daily loss of 65Zn than those given water, beer or cider. The ethanol group also showed a lower rate of 65Zn loss compared with the water group. The observed changes in whole-body 65Zn retention could be explained by an adverse influence of ethanol on Zn absorption from the diet. 4. Blood Hb and testes Zn concentration were similar in all groups but the type of liquid consumed influenced liver Fe levels. The cider group had the lowest liver Fe values and the ethanol group the highest values. 5. It is apparent from the present study that ethanol and alcoholic beverages affect Zn and Fe metabolism, but that the effects of ethanol are moderated by other components of the alcoholic beverages. Copyright © The Nutrition Society 1988 Fairweather-Tait Susan J. AFRC Institute of Food Research, Colney Lane, Norwich NR4 7UA Southon Susan AFRC Institute of Food Research, Colney Lane, Norwich NR4 7UA Piper Zoe AFRC Institute of Food Research, Colney Lane, Norwich NR4 7UA British Journal of Nutrition Cambridge University Press 60/2(1988-09), 209-215 0007-1145 60:2<209 1988 60 BJN https://doi.org/10.1079/BJN19880092 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1079/BJN19880092 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fairweather-Tait Susan J. AFRC Institute of Food Research, Colney Lane, Norwich NR4 7UA NATIONALLICENCE 700 1- Southon Susan AFRC Institute of Food Research, Colney Lane, Norwich NR4 7UA NATIONALLICENCE 700 1- Piper Zoe AFRC Institute of Food Research, Colney Lane, Norwich NR4 7UA NATIONALLICENCE 773 0- British Journal of Nutrition Cambridge University Press 60/2(1988-09), 209-215 0007-1145 60:2<209 1988 60 BJN CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge